Assessing the Global Impact of Brain Small Vessel Disease on Cognition: The Multi-Ethnic Study of Atherosclerosis.

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Title: Assessing the Global Impact of Brain Small Vessel Disease on Cognition: The Multi-Ethnic Study of Atherosclerosis.
Authors: Charisis S; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Rashid T; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA., Dintica C; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA., Gonzales M; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Neurology, Cedars Sinai Medical Center, Los Angeles, California, USA., Liu H; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Center for Advanced Imaging Research (CAIR), University of Maryland School of Medicine, Baltimore, Maryland, USA., Ware JB; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Austin TR; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA., Jensen PN; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA., Fohner AE; Department of Epidemiology, University of Washington, Seattle, Washington, USA., Tanley JE; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Ding J; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Luchsinger JA; Departments of Medicine and Epidemiology, Columbia University Medical Center, New York, New York, USA., Sachs B; Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Nasrallah IM; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; AI2D Center for AI and Data Science for Integrated Diagnostics, and Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Bryan RN; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Hayden KM; Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA., Wolk D; Alzheimer's Disease Research Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Rascovsky K; Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Davatzikos C; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; AI2D Center for AI and Data Science for Integrated Diagnostics, and Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Longstreth WT Jr; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA., Yaffe K; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA., Seshadri S; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA., Heckbert SR; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA., Hughes T; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Habes M; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; AI2D Center for AI and Data Science for Integrated Diagnostics, and Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Jun; Vol. 21 (6), pp. e70326.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: Assessing the Global Impact of Brain Small Vessel Disease on Cognition: The Multi-Ethnic Study of Atherosclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Charisis+S%22">Charisis S</searchLink>; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Rashid+T%22">Rashid T</searchLink>; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Dintica+C%22">Dintica C</searchLink>; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Gonzales+M%22">Gonzales M</searchLink>; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Neurology, Cedars Sinai Medical Center, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Center for Advanced Imaging Research (CAIR), University of Maryland School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Ware+JB%22">Ware JB</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Austin+TR%22">Austin TR</searchLink>; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Jensen+PN%22">Jensen PN</searchLink>; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Fohner+AE%22">Fohner AE</searchLink>; Department of Epidemiology, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Tanley+JE%22">Tanley JE</searchLink>; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Ding+J%22">Ding J</searchLink>; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Luchsinger+JA%22">Luchsinger JA</searchLink>; Departments of Medicine and Epidemiology, Columbia University Medical Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Sachs+B%22">Sachs B</searchLink>; Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Nasrallah+IM%22">Nasrallah IM</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; AI2D Center for AI and Data Science for Integrated Diagnostics, and Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bryan+RN%22">Bryan RN</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hayden+KM%22">Hayden KM</searchLink>; Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Wolk+D%22">Wolk D</searchLink>; Alzheimer's Disease Research Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Rascovsky+K%22">Rascovsky K</searchLink>; Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Davatzikos+C%22">Davatzikos C</searchLink>; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; AI2D Center for AI and Data Science for Integrated Diagnostics, and Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Longstreth+WT+Jr%22">Longstreth WT Jr</searchLink>; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Yaffe+K%22">Yaffe K</searchLink>; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Seshadri+S%22">Seshadri S</searchLink>; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Heckbert+SR%22">Heckbert SR</searchLink>; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Hughes+T%22">Hughes T</searchLink>; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Habes+M%22">Habes M</searchLink>; Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; AI2D Center for AI and Data Science for Integrated Diagnostics, and Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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