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Effect of metformin on hypoxia-associated gene expression in oral cavity squamous cell carcinoma in non-diabetic patients - a prospective window of opportunity study.

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Title: Effect of metformin on hypoxia-associated gene expression in oral cavity squamous cell carcinoma in non-diabetic patients - a prospective window of opportunity study.
Authors: Mueller SA; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. simon.mueller@usz.ch.; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland. simon.mueller@usz.ch., Elicin O; Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Monney B; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland., Rau T; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland.; Institute of Pathology, University Clinic Duesseldorf, Duesseldorf, Germany., Pra AD; Department of Radiation Oncology, University of Miami Health System, Coral Gables, FL, USA., Sachs L; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Ramos IC; Department of Radiation Oncology, University of Miami Health System, Coral Gables, FL, USA., Vassella E; Department of Radiation Oncology, University of Miami Health System, Coral Gables, FL, USA., Dammann F; Interventional and Pediatric Radiology, University Institute of Diagnostic, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Caparrotti F; Générale-Beaulieu Swiss Oncology Network, Geneva, Switzerland., Limacher A; Department of Clinical Research, CTU Bern, University of Bern, Bern, Switzerland., Nisa L; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Dettmer MS; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland.; Institute of Pathology, Klinikum Stuttgart Katharinenhospital, Stuttgart, Germany., Giger R; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Source: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2025 Sep; Vol. 282 (9), pp. 4773-4784. Date of Electronic Publication: 2025 Jun 04.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9002937 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-4726 (Electronic) Linking ISSN: 09374477 NLM ISO Abbreviation: Eur Arch Otorhinolaryngol Subsets: MEDLINE
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  Data: Effect of metformin on hypoxia-associated gene expression in oral cavity squamous cell carcinoma in non-diabetic patients - a prospective window of opportunity study.
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  Data: <searchLink fieldCode="AU" term="%22Mueller+SA%22">Mueller SA</searchLink>; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. simon.mueller@usz.ch.; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland. simon.mueller@usz.ch.<br /><searchLink fieldCode="AU" term="%22Elicin+O%22">Elicin O</searchLink>; Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Monney+B%22">Monney B</searchLink>; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for BioMedical Research, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rau+T%22">Rau T</searchLink>; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland.; Institute of Pathology, University Clinic Duesseldorf, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Pra+AD%22">Pra AD</searchLink>; Department of Radiation Oncology, University of Miami Health System, Coral Gables, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sachs+L%22">Sachs L</searchLink>; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ramos+IC%22">Ramos IC</searchLink>; Department of Radiation Oncology, University of Miami Health System, Coral Gables, FL, USA.<br /><searchLink fieldCode="AU" term="%22Vassella+E%22">Vassella E</searchLink>; Department of Radiation Oncology, University of Miami Health System, Coral Gables, FL, USA.<br /><searchLink fieldCode="AU" term="%22Dammann+F%22">Dammann F</searchLink>; Interventional and Pediatric Radiology, University Institute of Diagnostic, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Caparrotti+F%22">Caparrotti F</searchLink>; Générale-Beaulieu Swiss Oncology Network, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Limacher+A%22">Limacher A</searchLink>; Department of Clinical Research, CTU Bern, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nisa+L%22">Nisa L</searchLink>; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dettmer+MS%22">Dettmer MS</searchLink>; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland.; Institute of Pathology, Klinikum Stuttgart Katharinenhospital, Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Giger+R%22">Giger R</searchLink>; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
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