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Ischaemic endothelial necroptosis induces haemolysis and COVID-19 angiopathy.

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Title: Ischaemic endothelial necroptosis induces haemolysis and COVID-19 angiopathy.
Authors: Wu MCL; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Italiano E; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Jarvis-Child R; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia., Alwis I; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia., Smythe R; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Albornoz EA; School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, Australia., Noonan J; Atherothrombosis and Vascular Biology Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia., Portelli M; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Baptista M; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Maclean J; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Noori P; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Yang J; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia., Lee JD; School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, Australia., McFadyen JD; Atherothrombosis and Vascular Biology Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.; Department of Clinical Haematology, Alfred Hospital, Melbourne, Victoria, Australia., Sharland AF; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; Sydney Medical School, University of Sydney, Camperdown, New South Wales, Australia., Woodruff TM; School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, Australia., Samson AL; Walter and Eliza Hall Research Institute (WEHI), Parkville, Victoria, Australia.; University of Melbourne, Parkville, Victoria, Australia., Rapkiewicz A; New York University Winthrop Hospital, Department of Pathology, Long Island School of Medicine, Mineola, NY, USA., Barrett TJ; Grossman School of Medicine, New York University, New York, NY, USA., Pham A; Department of Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria, Australia., Schoenwaelder SM; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia.; School of Medical Sciences, University of Sydney, Camperdown, New South Wales, Australia., Yuan Y; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia., Jackson SP; The Heart Research Institute, Sydney, New South Wales, Australia. shaun.jackson@thrombio.com.au.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia. shaun.jackson@thrombio.com.au.; ThromBio, Sydney, New South Wales, Australia. shaun.jackson@thrombio.com.au.; Department of Molecular Medicine, MERU-Roon Research Center on Vascular Biology, The Scripps Research Institute, La Jolla, CA, USA. shaun.jackson@thrombio.com.au.
Source: Nature [Nature] 2025 Jul; Vol. 643 (8070), pp. 182-191. Date of Electronic Publication: 2025 Jun 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wu+MCL%22">Wu MCL</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Italiano+E%22">Italiano E</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Jarvis-Child+R%22">Jarvis-Child R</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Alwis+I%22">Alwis I</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Smythe+R%22">Smythe R</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Albornoz+EA%22">Albornoz EA</searchLink>; School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Noonan+J%22">Noonan J</searchLink>; Atherothrombosis and Vascular Biology Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Portelli+M%22">Portelli M</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Baptista+M%22">Baptista M</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Maclean+J%22">Maclean J</searchLink>; 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The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia.; School of Medical Sciences, University of Sydney, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Yuan+Y%22">Yuan Y</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia.; ThromBio, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Jackson+SP%22">Jackson SP</searchLink>; The Heart Research Institute, Sydney, New South Wales, Australia. shaun.jackson@thrombio.com.au.; Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia. shaun.jackson@thrombio.com.au.; ThromBio, Sydney, New South Wales, Australia. shaun.jackson@thrombio.com.au.; Department of Molecular Medicine, MERU-Roon Research Center on Vascular Biology, The Scripps Research Institute, La Jolla, CA, USA. shaun.jackson@thrombio.com.au.
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