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Epistasis regulates genetic control of cardiac hypertrophy.

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Title: Epistasis regulates genetic control of cardiac hypertrophy.
Authors: Wang Q; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA., Tang TM; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA.; Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN, USA., Youlton M; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.; Department of Molecular Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, USA., Weldy CS; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA., Kenney AM; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA.; Department of Statistics, University of California Irvine, Irvine, CA, USA., Ronen O; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA., Hughes JW; Department of Computer Science, Stanford University, Stanford, CA, USA., Chin ET; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.; Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA., Sutton SC; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA., Agarwal A; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA., Li X; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA., Behr M; Faculty of Informatics and Data Science, University of Regensburg, Regensburg, Germany., Kumbier K; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA., Moravec CS; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Tang WHW; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.; Department of Cardiovascular Medicine, Heart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA., Margulies KB; Division of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Cappola TP; Division of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Butte AJ; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA., Arnaout R; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA., Brown JB; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Division of Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Priest JR; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Tenaya Therapeutics, San Francisco, CA, USA., Parikh VN; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA., Yu B; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA. binyu@berkeley.edu.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA. binyu@berkeley.edu.; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA. binyu@berkeley.edu.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. binyu@berkeley.edu., Ashley EA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA. euan@stanford.edu.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA. euan@stanford.edu.
Source: Nature cardiovascular research [Nat Cardiovasc Res] 2025 Jun; Vol. 4 (6), pp. 740-760. Date of Electronic Publication: 2025 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918284280206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-0590 (Electronic) Linking ISSN: 27310590 NLM ISO Abbreviation: Nat Cardiovasc Res Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tang+TM%22">Tang TM</searchLink>; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA.; Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN, USA.<br /><searchLink fieldCode="AU" term="%22Youlton+M%22">Youlton M</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.; Department of Molecular Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Weldy+CS%22">Weldy CS</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kenney+AM%22">Kenney AM</searchLink>; 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Department of Statistics, University of California, Berkeley, Berkeley, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Division of Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Priest+JR%22">Priest JR</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Tenaya Therapeutics, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Parikh+VN%22">Parikh VN</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; Department of Statistics, University of California, Berkeley, Berkeley, CA, USA. binyu@berkeley.edu.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA. binyu@berkeley.edu.; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA. binyu@berkeley.edu.; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. binyu@berkeley.edu.<br /><searchLink fieldCode="AU" term="%22Ashley+EA%22">Ashley EA</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA, USA. euan@stanford.edu.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA. euan@stanford.edu.
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