Inflamed Microglia like Macrophages in the Central Nervous System of Prodromal Parkinson's Disease.

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Title: Inflamed Microglia like Macrophages in the Central Nervous System of Prodromal Parkinson's Disease.
Authors: Zhang L; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA., Yasumizu Y; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA., Deerhake ME; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA., Moon J; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06510, USA., Buitrago-Pocasangre N; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA., Russo A; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA., Wang H; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA., Zhu B; Department of Biostatistics, Yale School of Public Health, New Haven, CT, 06510, USA.; Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT 06510, USA., Seibyl JP; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA., Reddy V; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA., Wang Q; Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge, UK., Spillantini MG; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Clinical Neurosciences, University of Cambridge Department of Medicine, Cambridge, UK., Posner DA; Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge, UK., Clatworthy M; Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge, UK., Sumida TS; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06510, USA., Longbrake EE; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA., Cedarbaum JM; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA., Hafler DA; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06510, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 May 21. Date of Electronic Publication: 2025 May 21.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.<br /><searchLink fieldCode="AU" term="%22Yasumizu+Y%22">Yasumizu Y</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Deerhake+ME%22">Deerhake ME</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Moon+J%22">Moon J</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Buitrago-Pocasangre+N%22">Buitrago-Pocasangre N</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Russo+A%22">Russo A</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+B%22">Zhu B</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT, 06510, USA.; Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Seibyl+JP%22">Seibyl JP</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Reddy+V%22">Reddy V</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Spillantini+MG%22">Spillantini MG</searchLink>; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Clinical Neurosciences, University of Cambridge Department of Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Posner+DA%22">Posner DA</searchLink>; Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Clatworthy+M%22">Clatworthy M</searchLink>; Molecular Immunity Unit, University of Cambridge Department of Medicine, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Sumida+TS%22">Sumida TS</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Longbrake+EE%22">Longbrake EE</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Cedarbaum+JM%22">Cedarbaum JM</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.<br /><searchLink fieldCode="AU" term="%22Hafler+DA%22">Hafler DA</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT, 06510, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.; Department of Immunobiology, Yale School of Medicine, New Haven, CT, 06510, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
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