TANGO2 binds crystallin alpha B and its loss causes desminopathy.
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| Title: | TANGO2 binds crystallin alpha B and its loss causes desminopathy. |
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| Authors: | Stentenbach M; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Hughes LA; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Fagan SV; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Payne B; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Rudler DL; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Siira SJ; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., McCubbin T; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, Australia.; ARC Centre of Excellence in Synthetic Biology, The University of Queensland, St Lucia, QLD, Australia., Chopin A; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Perks KL; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia., Ermer JA; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Hendry J; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Er TS; School of Human Sciences, The University of Western Australia, Crawley, WA, Australia., Balasubramaniam S; Genetic Metabolic Disorders Service, The Children's Hospital at Westmead, Sydney, NSW, Australia.; Discipline of Genomic Medicine, Sydney Medical School, University of Sydney, Sydney, NSW, Australia., Eliades JA; Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia., Hool LC; School of Human Sciences, The University of Western Australia, Crawley, WA, Australia.; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia., Packer NH; ARC Centre of Excellence in Synthetic Biology, Macquarie University, Sydney, NSW, Australia.; School of Natural Sciences, Macquarie University, Sydney, NSW, Australia., Moh ESX; ARC Centre of Excellence in Synthetic Biology, Macquarie University, Sydney, NSW, Australia.; School of Natural Sciences, Macquarie University, Sydney, NSW, Australia., Padman BS; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia., Rackham O; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia. oliver.rackham@curtin.edu.au.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia. oliver.rackham@curtin.edu.au.; ARC Centre of Excellence in Synthetic Biology, The University of Queensland, St Lucia, QLD, Australia. oliver.rackham@curtin.edu.au.; Curtin Medical School, Curtin University, Bentley, WA, Australia. oliver.rackham@curtin.edu.au.; Curtin Medical Research Institute, Curtin University, Bentley, WA, Australia. oliver.rackham@curtin.edu.au., Filipovska A; The Kids Research Institute Australia, Northern Entrance, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA, Australia. aleksandra.filipovska@uwa.edu.au.; ARC Centre of Excellence in Synthetic Biology, University of Western Australia, Crawley, WA, Australia. aleksandra.filipovska@uwa.edu.au.; Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia. aleksandra.filipovska@uwa.edu.au.; Curtin Medical Research Institute, Curtin University, Bentley, WA, Australia. aleksandra.filipovska@uwa.edu.au. |
| Source: | Nature communications [Nat Commun] 2025 Jun 06; Vol. 16 (1), pp. 5261. Date of Electronic Publication: 2025 Jun 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-60563-1 |
