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Quantitation of PET spatial extent as a potential adjunct to visual interpretation of [18F]flortaucipir imaging: TAU-SPEX.

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Title: Quantitation of PET spatial extent as a potential adjunct to visual interpretation of [18F]flortaucipir imaging: TAU-SPEX.
Authors: Coomans EM; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands. e.coomans@amsterdamumc.nl.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands. e.coomans@amsterdamumc.nl., van Tol B; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Groot C; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Smith R; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Stomrud E; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Pontecorvo MJ; Eli Lilly and Company, Indianapolis, IN, USA., Shcherbinin S; Eli Lilly and Company, Indianapolis, IN, USA., Kennedy I; Eli Lilly and Company, Indianapolis, IN, USA., Kotari V; Eli Lilly and Company, Indianapolis, IN, USA., van der Flier WM; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Pijnenburg YAL; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden., van de Giessen E; Radiology & Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands., Ossenkoppele R; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands. r.ossenkoppele@amsterdamumc.nl.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands. r.ossenkoppele@amsterdamumc.nl.; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden. r.ossenkoppele@amsterdamumc.nl.
Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2025 Nov; Vol. 52 (13), pp. 5135-5149. Date of Electronic Publication: 2025 Jun 07.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE
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  Data: Quantitation of PET spatial extent as a potential adjunct to visual interpretation of [<superscript>18</superscript>F]flortaucipir imaging: TAU-SPEX.
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  Data: <searchLink fieldCode="AU" term="%22Coomans+EM%22">Coomans EM</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands. e.coomans@amsterdamumc.nl.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands. e.coomans@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22van+Tol+B%22">van Tol B</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Groot+C%22">Groot C</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smith+R%22">Smith R</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Palmqvist+S%22">Palmqvist S</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Stomrud+E%22">Stomrud E</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Pontecorvo+MJ%22">Pontecorvo MJ</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Shcherbinin+S%22">Shcherbinin S</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Kennedy+I%22">Kennedy I</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Kotari+V%22">Kotari V</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22van+der+Flier+WM%22">van der Flier WM</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pijnenburg+YAL%22">Pijnenburg YAL</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mattsson-Carlgren+N%22">Mattsson-Carlgren N</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22van+de+Giessen+E%22">van de Giessen E</searchLink>; Radiology & Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ossenkoppele+R%22">Ossenkoppele R</searchLink>; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands. r.ossenkoppele@amsterdamumc.nl.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands. r.ossenkoppele@amsterdamumc.nl.; Clinical Memory Research Unit, Department of Clinical Sciences in Malmö, Lund University, Lund, Sweden. r.ossenkoppele@amsterdamumc.nl.
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