Effectiveness of perampanel as only concomitant antiseizure medication for highly active epilepsy: insight from a real-world, multicenter retrospective study.
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| Title: | Effectiveness of perampanel as only concomitant antiseizure medication for highly active epilepsy: insight from a real-world, multicenter retrospective study. |
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| Authors: | Pascarella A; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy.; Regional Epilepsy Centre, Great Metropolitan 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy., Pasquale M; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy.; Regional Epilepsy Centre, Great Metropolitan 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy., Abelardo D; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy.; Regional Epilepsy Centre, Great Metropolitan 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy., Gasparini S; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy.; Regional Epilepsy Centre, Great Metropolitan 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy., Marsico O; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy., Cutellè R; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy.; Regional Epilepsy Centre, Great Metropolitan 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy., Cianci V; Neurology Unit, 'Great Metropolitan 'Bianchi-Melacrino-Morelli Hospital', Reggio Calabria, Italy., Iudice A; Department of Neurosciences, Section of Neurology, University of Pisa, Pisa, Italy., Bisulli F; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.; Full Member of the European Reference Network for Rare and Complex Epilepsies (EpiCARE), IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy., Bonanni P; Epilepsy and Clinical Neurophysiology Unit, Scientific Institute, IRCCS Eugenio Medea, Conegliano, Treviso, Italy., Caggia E; Neurology Unit, Ospedale Giovanni Paolo II, Ragusa, Italy., D'Aniello A; IRCCS Neuromed, Pozzilli, Italy., Di Bonaventura C; Epilepsy Unit, Department of Human Neurosciences, 'Sapienza' University of Rome, Rome, Italy., DiFrancesco JC; Department of Neurology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Domina E; U.C. Neurology, Ospedale Maggiore di Lodi ASST, Lodi, Italy., Dono F; Department of Neuroscience, Imaging and Clinical Science, 'G. D'Annunzio' University of Chieti-Pescara, Chieti, Italy., Gambardella A; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy.; Neurologic Clinic, Magna Græcia University of Catanzaro, Catanzaro, Italy., Marini C; Child Neurology and Psychiatric Unit, G. Salesi Pediatric Hospital, Azienda Ospedaliera-Universitaria delle Marche, Ancona, Italy., Marrelli A; Neurophysiopathology Unit, Epilepsy Center, San Salvatore Hospital, L'Aquila, Italy., Matricardi S; Department of Pediatrics, University of Chieti, Chieti, Italy., Morano A; Epilepsy Unit, Department of Human Neurosciences, 'Sapienza' University of Rome, Rome, Italy., Paladin F; Neurology Unit, Epilepsy Center, Venice, Italy., Renna R; Neurological Clinic and Stroke Unit, AORN San Pio, Benevento, Italy., Piccioli M; UOC Neurology, PO San Filippo Neri, ASL Roma 1, Rome, Italy., Striano P; Full member of ERN-EPICARE, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy., Ascoli M; Neurology Unit, Marche Nord Hospital, Pesaro, Italy., La Neve A; Dipartimento di Scienze Mediche di Base, Neuroscienze e Organi di Senso, Università di Bari, Bari, Italy., Le Piane E; Dipartimento di Neurologia, Ospedale Pugliese-Ciaccio, Catanzaro, Italy., Orsini A; Pediatric Neurology, Pediatric Department, AOUP Santa Chiara Univeristy Hospital, Pisa, Italy., Torino C; Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension of Reggio Calabria, National Research Council, Institute of Clinical Physiology, Reggio Calabria, Italy., Beretta S; Department of Neurology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Aguglia U; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy.; Regional Epilepsy Centre, Great Metropolitan 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy., Ferlazzo E; Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Italy. ferlazzo@unicz.it.; Regional Epilepsy Centre, Great Metropolitan 'Bianchi-Melacrino-Morelli' Hospital, Reggio Calabria, Italy. ferlazzo@unicz.it. |
| Corporate Authors: | PEROC Study Group |
| Source: | Journal of neurology [J Neurol] 2025 Jun 07; Vol. 272 (7), pp. 449. Date of Electronic Publication: 2025 Jun 07. |
| Publication Type: | Journal Article; Multicenter Study; Observational Study |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-1459 |
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| DOI: | 10.1007/s00415-025-13184-z |
