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Infliximab Pharmacokinetics, Dosing, and Response in Hospitalized Patients with COVID-19 Pneumonia: A Secondary Analysis of a Multinational Randomized Clinical Trial (ACTIV-1 IM).

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Title: Infliximab Pharmacokinetics, Dosing, and Response in Hospitalized Patients with COVID-19 Pneumonia: A Secondary Analysis of a Multinational Randomized Clinical Trial (ACTIV-1 IM).
Authors: Balevic SJ; Duke Clinical Research Institute, Durham, NC, USA.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Gonzalez D; Duke Clinical Research Institute, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Smith PB; Duke Clinical Research Institute, Durham, NC, USA.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Powderly WG; Department of Medicine, Washington University St. Louis, St. Louis, MO, USA., Schmid A; Deptartment of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA., Kang A; Hackensack University Medical Center, Hackensack, NJ, USA., McCarthy MW; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Shaw LK; Duke Clinical Research Institute, Durham, NC, USA., Lindsell CJ; Duke Clinical Research Institute, Durham, NC, USA., Bozzette S; National Center for Advancing Translational Sciences, Bethesda, MD, USA., Hoetelmans RMW; Johnson & Johnson Innovative Medicine, Beerse, Belgium., Hornik CP; Duke Clinical Research Institute, Durham, NC, USA.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA., Benjamin DK Jr; Duke Clinical Research Institute, Durham, NC, USA.; Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Corporate Authors: ACTIV‐1 IM Study Group Members
Source: Journal of clinical pharmacology [J Clin Pharmacol] 2025 Nov; Vol. 65 (11), pp. 1497-1505. Date of Electronic Publication: 2025 Jun 09.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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