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Impact of mtG3PDH inhibitors on proliferation and metabolism of androgen receptor-negative prostate cancer cells: Role of extracellular pyruvate.

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Title: Impact of mtG3PDH inhibitors on proliferation and metabolism of androgen receptor-negative prostate cancer cells: Role of extracellular pyruvate.
Authors: Di Paola FJ; Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Cardoso LH; Oroboros Instruments, Schoepfstrasse 18, Innsbruck, Austria., Nikitopoulou E; Medical Research Council Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, United Kingdom., Kulik B; Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany., Rühl S; Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany., Eva A; Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany., Sommer N; Excellence Cluster Cardio-Pulmonary Institute (CPI), University of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus Liebig University, Giessen, Germany., Linn T; Clinical Research Unit, Center of Internal Medicine, Justus Liebig University, Giessen, Germany., Gnaiger E; Oroboros Instruments, Schoepfstrasse 18, Innsbruck, Austria., Failing K; Unit for Biomathematics and Data Processing, Veterinary Faculty, Justus Liebig University of Giessen, Giessen, Germany., Büttner K; Unit for Biomathematics and Data Processing, Veterinary Faculty, Justus Liebig University of Giessen, Giessen, Germany., Frezza C; Medical Research Council Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, United Kingdom.; Faculty of Medicine and University Hospital Cologne, Faculty of Mathematics and Natural Sciences, Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany., Mazurek S; Institute of Veterinary Physiology and Biochemistry, Justus Liebig University of Giessen, Giessen, Germany.
Source: PloS one [PLoS One] 2025 Jun 09; Vol. 20 (6), pp. e0325509. Date of Electronic Publication: 2025 Jun 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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