Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease.

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Title: Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease.
Authors: Mecca AP; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Ashton NJ; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Chen MK; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA., O'Dell RS; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Toyonaga T; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA., Zhao W; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Young JJ; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Salardini E; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Bates KA; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Ra J; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Goodcase S; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Silva-Rudberg JA; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA., Nabulsi NB; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA., Brinkmalm A; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Kvartsberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Lab, Sahlgrenska University Hospital, Mölndal, Sweden., Schöll M; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Nilsson J; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Arnsten AFT; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA., Huang Y; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Lab, Sahlgrenska University Hospital, Mölndal, Sweden., Carson RE; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Lab, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, China., van Dyck CH; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Jun; Vol. 21 (6), pp. e70344.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Mecca+AP%22">Mecca AP</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Ashton+NJ%22">Ashton NJ</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Chen+MK%22">Chen MK</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22O'Dell+RS%22">O'Dell RS</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Toyonaga+T%22">Toyonaga T</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Young+JJ%22">Young JJ</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Salardini+E%22">Salardini E</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Bates+KA%22">Bates KA</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Ra+J%22">Ra J</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Goodcase+S%22">Goodcase S</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Silva-Rudberg+JA%22">Silva-Rudberg JA</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Nabulsi+NB%22">Nabulsi NB</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Brinkmalm+A%22">Brinkmalm A</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Kvartsberg+H%22">Kvartsberg H</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Lab, Sahlgrenska University Hospital, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Schöll+M%22">Schöll M</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Nilsson+J%22">Nilsson J</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Arnsten+AFT%22">Arnsten AFT</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Lab, Sahlgrenska University Hospital, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Carson+RE%22">Carson RE</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Lab, Sahlgrenska University Hospital, Mölndal, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, China.<br /><searchLink fieldCode="AU" term="%22van+Dyck+CH%22">van Dyck CH</searchLink>; Alzheimer's Disease Research Unit, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Neuroscience, Yale School of Medicine, New Haven, Connecticut, USA.; Department of Neurology, Yale School of Medicine, New Haven, Connecticut, USA.
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