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Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes.

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Title: Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes.
Authors: Assary E; School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK. elham.1.assary@kcl.ac.uk.; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. elham.1.assary@kcl.ac.uk., Coleman JRI; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK., Hemani G; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK., van de Weijer MP; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Howe LJ; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Palviainen T; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Grasby KL; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.; School of Biomedical Sciences, University of Queensland, Brisbane, Queensland, Australia., Ahlskog R; Department of Government, Uppsala University, Uppsala, Sweden., Nygaard M; The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Cheesman R; The PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway., Lim K; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Reynolds CA; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA.; Department of Psychology, University of California, Riverside, Riverside, CA, USA.; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA., Ordoñana JR; Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, Spain.; Biomedical Research Institute of Murcia (IMIB-Arrixaca), Murcia, Spain., Colodro-Conde L; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, Spain.; School of Psychology, University of Queensland, Brisbane, Queensland, Australia., Gordon S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Madrid-Valero JJ; Department of Human Anatomy and Psychobiology, University of Murcia, Murcia, Spain.; Biomedical Research Institute of Murcia (IMIB-Arrixaca), Murcia, Spain., Thalamuthu A; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Mengel-From J; The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Armstrong NJ; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; School of Electrical Engineering, Computing and Mathematical Sciences, Curtin University, Perth, Western Australia, Australia., Sachdev PS; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Lee T; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Brodaty H; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Trollor JN; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; National Centre of Excellence in Intellectual Disability Health, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Wright M; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Ames D; University of Melbourne Academic Unit for Psychiatry of Old Age, St George's Hospital, Melbourne, Victoria, Australia., Catts VS; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Latvala A; Institute of Criminology and Legal Policy, University of Helsinki, Helsinki, Finland., Vuoksimaa E; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Mallard T; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Center for Precision Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Paige Harden K; Department of Psychology and Population Research Center, University of Texas at Austin, Austin, TX, USA., Tucker-Drob EM; Department of Psychology and Population Research Center, University of Texas at Austin, Austin, TX, USA., Oskarsson S; Department of Government, Uppsala University, Uppsala, Sweden., Hammond CJ; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Christensen K; The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.; Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark., Taylor M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Lundström S; Gillberg Neuropsychiatry Centre, University of Gothenburg, Gothenburg, Sweden.; Office for Psychiatry, Habilitation and Aid, Child and Adolescent Mental Health Services, Malmö, Sweden., Larsson H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Mather KA; Centre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Boomsma DI; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Reproduction and Development research institute, Amsterdam, the Netherlands., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Plomin R; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Bartels M; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Lichtenstein P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Kaprio J; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Eley TC; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK., Davies NM; Division of Psychiatry, University College London, London, UK.; Department of Statistical Science, University College London, London, UK., Munroe PB; William Harvey Research Institute, Queen Mary University of London, London, UK., Keers R; School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK.
Corporate Authors: Within Family Consortium
Source: Nature human behaviour [Nat Hum Behav] 2025 Aug; Vol. 9 (8), pp. 1683-1696. Date of Electronic Publication: 2025 Jun 10.
Publication Type: Journal Article; Twin Study; Meta-Analysis
Journal Info: Publisher: Springer Nature Publishing Country of Publication: England NLM ID: 101697750 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2397-3374 (Electronic) Linking ISSN: 23973374 NLM ISO Abbreviation: Nat Hum Behav Subsets: MEDLINE
Database: MEDLINE Ultimate
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          Name:
            NameFull: Boomsma DI
      – PersonEntity:
          Name:
            NameFull: Martin NG
      – PersonEntity:
          Name:
            NameFull: Plomin R
      – PersonEntity:
          Name:
            NameFull: Bartels M
      – PersonEntity:
          Name:
            NameFull: Lichtenstein P
      – PersonEntity:
          Name:
            NameFull: Kaprio J
      – PersonEntity:
          Name:
            NameFull: Eley TC
      – PersonEntity:
          Name:
            NameFull: Davies NM
      – PersonEntity:
          Name:
            NameFull: Munroe PB
      – PersonEntity:
          Name:
            NameFull: Keers R
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 08
              Text: 2025 Aug
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2397-3374
          Numbering:
            – Type: volume
              Value: 9
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Nature human behaviour
              Type: main
ResultId 1