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Differential susceptibility and role for senescence in CART cells based on costimulatory domains.

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Title: Differential susceptibility and role for senescence in CART cells based on costimulatory domains.
Authors: Can I; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Siegler EL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Sirpilla OL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Manriquez-Roman C; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Center for Regenerative Biotherapeutics, Mayo Clinic, Rochester, MN, USA., Yun K; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Stewart CM; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Feigin JM; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Rodriguez ML; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Gutierrez-Ruiz OL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Ogbodo EJ; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Huynh TN; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Kimball BL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Mai LK; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Hefazi M; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Fonkoua LK; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Xia H; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Hamaidi I; Cancer Biology, Mayo Clinic, Jacksonville, FL, USA., Alkan B; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye., Sezer F; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye., Ekiz HA; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye., Sakemura RL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Kenderian SS; T Cell Engineering, Mayo Clinic, Rochester, MN, USA. kenderian.saad@mayo.edu.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA. kenderian.saad@mayo.edu.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA. kenderian.saad@mayo.edu.; Center for Regenerative Biotherapeutics, Mayo Clinic, Rochester, MN, USA. kenderian.saad@mayo.edu.
Source: Molecular cancer [Mol Cancer] 2025 Jun 10; Vol. 24 (1), pp. 172. Date of Electronic Publication: 2025 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Differential susceptibility and role for senescence in CART cells based on costimulatory domains.
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  Data: <searchLink fieldCode="AU" term="%22Can+I%22">Can I</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Siegler+EL%22">Siegler EL</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Sirpilla+OL%22">Sirpilla OL</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Manriquez-Roman+C%22">Manriquez-Roman C</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Center for Regenerative Biotherapeutics, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Yun+K%22">Yun K</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Stewart+CM%22">Stewart CM</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Feigin+JM%22">Feigin JM</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+ML%22">Rodriguez ML</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez-Ruiz+OL%22">Gutierrez-Ruiz OL</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Ogbodo+EJ%22">Ogbodo EJ</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Huynh+TN%22">Huynh TN</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Kimball+BL%22">Kimball BL</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Mai+LK%22">Mai LK</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Hefazi+M%22">Hefazi M</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Fonkoua+LK%22">Fonkoua LK</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Oncology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Xia+H%22">Xia H</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Hamaidi+I%22">Hamaidi I</searchLink>; Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Alkan+B%22">Alkan B</searchLink>; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye.<br /><searchLink fieldCode="AU" term="%22Sezer+F%22">Sezer F</searchLink>; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye.<br /><searchLink fieldCode="AU" term="%22Ekiz+HA%22">Ekiz HA</searchLink>; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye.<br /><searchLink fieldCode="AU" term="%22Sakemura+RL%22">Sakemura RL</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA.<br /><searchLink fieldCode="AU" term="%22Kenderian+SS%22">Kenderian SS</searchLink>; T Cell Engineering, Mayo Clinic, Rochester, MN, USA. kenderian.saad@mayo.edu.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA. kenderian.saad@mayo.edu.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA. kenderian.saad@mayo.edu.; Center for Regenerative Biotherapeutics, Mayo Clinic, Rochester, MN, USA. kenderian.saad@mayo.edu.
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  Data: <searchLink fieldCode="JN" term="%22101147698%22">Molecular cancer</searchLink> [Mol Cancer] 2025 Jun 10; Vol. 24 (1), pp. 172. <i>Date of Electronic Publication: </i>2025 Jun 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101147698 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214764598%22">14764598 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cancer <i>Subsets: </i>MEDLINE
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