Augmented Enteral Protein During Critical Illness: The TARGET Protein Randomized Clinical Trial.
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| Title: | Augmented Enteral Protein During Critical Illness: The TARGET Protein Randomized Clinical Trial. |
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| Authors: | Summers MJ; Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia.; Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia., Chapple LS; Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia.; Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.; Centre for Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, South Australia, Australia.; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia., Karahalios A; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.; Methods and Implementation Support for Clinical and Health research (MISCH) Hub, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia., Bellomo R; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; Intensive Care Unit, Austin Health, Heidelberg, Victoria, Australia.; Department of Critical Care, The University of Melbourne, Melbourne, Australia., Chapman MJ; Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia.; Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.; Centre for Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, South Australia, Australia.; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia., Ferrie S; Department of Nutrition & Dietetics, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.; Faculty of Medicine and Health, University of Sydney, Sydney, Australia., Finnis ME; Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia.; Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia.; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; Department of Critical Care, The University of Melbourne, Melbourne, Australia., French C; Department of Critical Care, The University of Melbourne, Melbourne, Australia.; Intensive Care Unit, Sunshine Hospital, Melbourne, Victoria, Australia., Hurford S; Medical Research Institute of New Zealand, Wellington, New Zealand., Kakho N; Intensive Care Unit, University Hospital Geelong, Geelong, Victoria, Australia., Maiden MJ; Department of Critical Care, The University of Melbourne, Melbourne, Australia.; Intensive Care Unit, University Hospital Geelong, Geelong, Victoria, Australia.; Intensive Care Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia., O'Connor SN; Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia.; Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia., Peake SL; Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia.; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; Department of Intensive Care Medicine, The Queen Elizabeth Hospital, Woodville South, South Australia, Australia., Presneill JJ; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; Department of Critical Care, The University of Melbourne, Melbourne, Australia.; Intensive Care Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia., Ridley EJ; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; Dietetics and Nutrition, Alfred Hospital, Melbourne, Victoria, Australia., Tran-Duy A; Methods and Implementation Support for Clinical and Health research (MISCH) Hub, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia.; Centre for Health Policy, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Williams PJ; Discipline of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, Australia.; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; Department of Intensive Care Medicine, The Queen Elizabeth Hospital, Woodville South, South Australia, Australia., Young PJ; Department of Critical Care, The University of Melbourne, Melbourne, Australia.; Intensive Care Unit, Sunshine Hospital, Melbourne, Victoria, Australia.; Intensive Care Unit, Wellington Hospital, Wellington, New Zealand., Zaloumis S; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.; Methods and Implementation Support for Clinical and Health research (MISCH) Hub, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia., Deane AM; Department of Critical Care, The University of Melbourne, Melbourne, Australia.; Intensive Care Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia. |
| Corporate Authors: | TARGET Protein Investigators and for the Australian and New Zealand Intensive Care Society Clinical Trials Group |
| Source: | JAMA [JAMA] 2025 Jul 22; Vol. 334 (4), pp. 319-328. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1538-3598 |
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| DOI: | 10.1001/jama.2025.9110 |
