Gut Microbiota Modulation through Akkermansia spp. Supplementation Increases CAR T-cell Potency.
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| Title: | Gut Microbiota Modulation through Akkermansia spp. Supplementation Increases CAR T-cell Potency. |
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| Authors: | Marcos-Kovandzic L; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Gustave Roussy Cancer Campus (GRCC), Clinicobiome, Villejuif, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Avagliano M; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy., Ben Khelil M; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France.; Hematology Department, Institut Gustave Roussy, Villejuif, France., Srikanthan J; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France.; Hematology Department, Institut Gustave Roussy, Villejuif, France., Abdallah R; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Petrocelli V; IFOM ETS, The AIRC Institute of Molecular Oncology, Milano, Italy., Rengassamy J; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France.; Hematology Department, Institut Gustave Roussy, Villejuif, France., Alfaro A; Gustave Roussy, UMS AMMICa, CNRS UAR3655, INSERM US23, Villejuif, France., Bied M; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Fidelle M; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Gustave Roussy Cancer Campus (GRCC), Clinicobiome, Villejuif, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Ferrere G; EverImmune, Gustave Roussy Cancer Center, Villejuif, France., Daillère R; EverImmune, Gustave Roussy Cancer Center, Villejuif, France., Arbab A; Biopathology Department, Institut Gustave Roussy, Villejuif, France., Amine-Hneineh R; Hematology Department, Institut Gustave Roussy, Villejuif, France., Pages A; Bureau de Biostatistique et d'Epidémiologie, Gustave Roussy et CESP U1018, Oncostat, labellisé Ligue Contre le Cancer, Inserm, Villejuif, France., Dartigues P; Biopathology Department, Institut Gustave Roussy, Villejuif, France., Ly P; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Simon S; Translational Sciences and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, Washington., Durand S; Metabolomics and Cell Biology Platforms UMS AMMICa/UMR 1138, Institut Gustave Roussy, Villejuif, France.; Equipe labellisée par la Ligue contre le cancer, Centre de Recherche des Cordeliers, Inserm U1138, Université de Paris, Sorbonne Université, Institut Universitaire de France, Paris, France., Gottschlich A; Department of Medicine III, Ludwig Maximilian University Hospital, Ludwig Maximilian University Munich, Munich, Germany.; Division of Clinical Pharmacology, Ludwig Maximilian University Hospital, Ludwig Maximilian University Munich, Member of the German Center for Lung Research, Munich, Germany.; Bavarian Cancer Research Center, Munich, Germany.; German Cancer Consortium, A Partnership Between Ludwig Maximilian University Hospital and German Cancer Consortium Heidelberg, Munich, Germany., Ginhoux F; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Blériot C; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Liu P; Metabolomics and Cell Biology Platforms UMS AMMICa/UMR 1138, Institut Gustave Roussy, Villejuif, France.; Equipe labellisée par la Ligue contre le cancer, Centre de Recherche des Cordeliers, Inserm U1138, Université de Paris, Sorbonne Université, Institut Universitaire de France, Paris, France., Zhao L; Metabolomics and Cell Biology Platforms UMS AMMICa/UMR 1138, Institut Gustave Roussy, Villejuif, France.; Equipe labellisée par la Ligue contre le cancer, Centre de Recherche des Cordeliers, Inserm U1138, Université de Paris, Sorbonne Université, Institut Universitaire de France, Paris, France., Creusot L; Paris Center for Microbiome Medicine (PaCeMM) FHU, AP-HP, Paris, France.; Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint Antoine Hospital, Gastroenterology Department, Sorbonne Universite, INSERM, Paris, France., Rolhion N; Paris Center for Microbiome Medicine (PaCeMM) FHU, AP-HP, Paris, France.; Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint Antoine Hospital, Gastroenterology Department, Sorbonne Universite, INSERM, Paris, France., Derosa L; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Gustave Roussy Cancer Campus (GRCC), Clinicobiome, Villejuif, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Kroemer G; Equipe labellisée par la Ligue contre le cancer, Centre de Recherche des Cordeliers, Inserm U1138, Université de Paris, Sorbonne Université, Institut Universitaire de France, Paris, France., Menger L; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Kobold S; Department of Medicine III, Ludwig Maximilian University Hospital, Ludwig Maximilian University Munich, Munich, Germany.; Bavarian Cancer Research Center, Munich, Germany.; German Cancer Consortium, A Partnership Between Ludwig Maximilian University Hospital and German Cancer Consortium Heidelberg, Munich, Germany., Castilla-Llorente C; Hematology Department, Institut Gustave Roussy, Villejuif, France., Sokol H; Paris Center for Microbiome Medicine (PaCeMM) FHU, AP-HP, Paris, France.; Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint Antoine Hospital, Gastroenterology Department, Sorbonne Universite, INSERM, Paris, France., Casola S; IFOM ETS, The AIRC Institute of Molecular Oncology, Milano, Italy.; Department of Medical Biotechnology and Translational Medicine, University of Milano, Milano, Italy., Pasolli E; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy., Zitvogel L; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Gustave Roussy Cancer Campus (GRCC), Clinicobiome, Villejuif, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France., Bigenwald C; Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.; Institut National de la Santé Et de la Recherche Medicale (INSERM) U1015, Institut Gustave Roussy, Villejuif, France.; Hematology Department, Institut Gustave Roussy, Villejuif, France. |
| Source: | Cancer discovery [Cancer Discov] 2025 Sep 04; Vol. 15 (9), pp. 1905-1926. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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