Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors.

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Title: Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors.
Authors: Mishra S; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Yadav MK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Dalal A; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Ganguly M; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Yadav R; Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.; The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA., Sawada K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Tiwari D; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Roy N; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Banerjee N; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Fung JN; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Marallag J; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Cui CS; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Li XX; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Lee JD; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Dsouza CA; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Saha S; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Sarma P; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Rawat G; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Zhu H; Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.; The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA., Khant HA; USC Center of Excellence for Nano-Imaging, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA., Clark RJ; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Banerjee R; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India., Woodruff TM; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Gati C; Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.; The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.; Department of Chemistry, University of Southern California, Los Angeles, CA, USA., Shukla AK; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 May 29. Date of Electronic Publication: 2025 May 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
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  Data: Molecular fingerprints of a convergent mechanism orchestrating diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptors.
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  Data: <searchLink fieldCode="AU" term="%22Mishra+S%22">Mishra S</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Yadav+MK%22">Yadav MK</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Dalal+A%22">Dalal A</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Ganguly+M%22">Ganguly M</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Yadav+R%22">Yadav R</searchLink>; Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.; The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sawada+K%22">Sawada K</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tiwari+D%22">Tiwari D</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Roy+N%22">Roy N</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Banerjee+N%22">Banerjee N</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Fung+JN%22">Fung JN</searchLink>; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Marallag+J%22">Marallag J</searchLink>; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Cui+CS%22">Cui CS</searchLink>; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Li+XX%22">Li XX</searchLink>; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Lee+JD%22">Lee JD</searchLink>; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Dsouza+CA%22">Dsouza CA</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Saha+S%22">Saha S</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Sarma+P%22">Sarma P</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Rawat+G%22">Rawat G</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.; The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Khant+HA%22">Khant HA</searchLink>; USC Center of Excellence for Nano-Imaging, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Clark+RJ%22">Clark RJ</searchLink>; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Sano+FK%22">Sano FK</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Banerjee+R%22">Banerjee R</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.<br /><searchLink fieldCode="AU" term="%22Woodruff+TM%22">Woodruff TM</searchLink>; School of Biomedical Sciences, Faculty of Health, Medicine, and Behavioural Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.<br /><searchLink fieldCode="AU" term="%22Nureki+O%22">Nureki O</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Gati+C%22">Gati C</searchLink>; Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.; The Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.; Department of Chemistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shukla+AK%22">Shukla AK</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.
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