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PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer.

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Title: PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer.
Authors: Young AA, Juhler IG, Pierce JR, Bohlin HE, Harper HA, Onishile DS, Chua RN, Liu ME, Gardner EN, Elzey BD, Cottrell KA
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 09. Date of Electronic Publication: 2025 Jun 09.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40501907
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Young+AA%22">Young AA</searchLink><br /><searchLink fieldCode="AU" term="%22Juhler+IG%22">Juhler IG</searchLink><br /><searchLink fieldCode="AU" term="%22Pierce+JR%22">Pierce JR</searchLink><br /><searchLink fieldCode="AU" term="%22Bohlin+HE%22">Bohlin HE</searchLink><br /><searchLink fieldCode="AU" term="%22Harper+HA%22">Harper HA</searchLink><br /><searchLink fieldCode="AU" term="%22Onishile+DS%22">Onishile DS</searchLink><br /><searchLink fieldCode="AU" term="%22Chua+RN%22">Chua RN</searchLink><br /><searchLink fieldCode="AU" term="%22Liu+ME%22">Liu ME</searchLink><br /><searchLink fieldCode="AU" term="%22Gardner+EN%22">Gardner EN</searchLink><br /><searchLink fieldCode="AU" term="%22Elzey+BD%22">Elzey BD</searchLink><br /><searchLink fieldCode="AU" term="%22Cottrell+KA%22">Cottrell KA</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Jun 09. <i>Date of Electronic Publication: </i>2025 Jun 09.
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  Data: Journal Article; Preprint
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40501907
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      – Type: doi
        Value: 10.1101/2025.05.27.656288
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer.
        Type: main
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            NameFull: Young AA
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          Dates:
            – D: 09
              M: 06
              Text: 2025 Jun 09
              Type: published
              Y: 2025
          Identifiers:
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              Value: 2692-8205
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            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
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