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NEXUS: a phase I dose escalation study of selinexor plus nivolumab and ipilimumab in Asian patients with advanced/metastatic solid malignancies.

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Title: NEXUS: a phase I dose escalation study of selinexor plus nivolumab and ipilimumab in Asian patients with advanced/metastatic solid malignancies.
Authors: R Choo J; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Jeraj SN; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Sundar R; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yong WP; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lee M; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Huang Y; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Asokumaran Y; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Chan GHJ; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Ngoi NYL; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, National University of Singapore, Singapore, Singapore., Wong ALA; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Soo RA; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Chee CE; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Lim JSJ; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore., Goh BC; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Lee SC; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Tan DSP; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, 1E Kent Ridge Road, National University Health System Tower Block Level 7, Singapore 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Source: Therapeutic advances in medical oncology [Ther Adv Med Oncol] 2025 Jun 09; Vol. 17, pp. 17588359251339930. Date of Electronic Publication: 2025 Jun 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Sage Country of Publication: England NLM ID: 101510808 Publication Model: eCollection Cited Medium: Print ISSN: 1758-8340 (Print) Linking ISSN: 17588340 NLM ISO Abbreviation: Ther Adv Med Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: NEXUS: a phase I dose escalation study of selinexor plus nivolumab and ipilimumab in Asian patients with advanced/metastatic solid malignancies.
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  Data: <searchLink fieldCode="AU" term="%22R+Choo+J%22">R Choo J</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Jeraj+SN%22">Jeraj SN</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Sundar+R%22">Sundar R</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yong+WP%22">Yong WP</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Asokumaran+Y%22">Asokumaran Y</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chan+GHJ%22">Chan GHJ</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ngoi+NYL%22">Ngoi NYL</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wong+ALA%22">Wong ALA</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Soo+RA%22">Soo RA</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chee+CE%22">Chee CE</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+JSJ%22">Lim JSJ</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Goh+BC%22">Goh BC</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+SC%22">Lee SC</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+DSP%22">Tan DSP</searchLink>; Department of Haematology-Oncology, National University Health System, National University Cancer Institute, 1E Kent Ridge Road, National University Health System Tower Block Level 7, Singapore 119228, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
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        Text: English
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      – TitleFull: NEXUS: a phase I dose escalation study of selinexor plus nivolumab and ipilimumab in Asian patients with advanced/metastatic solid malignancies.
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              Text: 2025 Jun 09
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