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Sustained oxygen-releasing hydrogel implants enhance flap regeneration by promoting mitochondrial biogenesis under mild hypoxia.

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Title: Sustained oxygen-releasing hydrogel implants enhance flap regeneration by promoting mitochondrial biogenesis under mild hypoxia.
Authors: Jeon S; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea.; Division of Pediatric Plastic Surgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 03080, Seoul, Republic of Korea., Jeong SH; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea.; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.; Institute of Medical and Biological Engineering, Bio-max Institute, Interdisciplinary Program in Bioengineering, Seoul National University, 08826, Seoul, Republic of Korea., Lee MH; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea., Seo JW; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA., Kim DS; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA., Bassous NJ; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA., Lozano Soto JA; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA., Choi C; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA., Gonzalez ML; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA., Nolasco Díaz EB; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.; Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Campus Monterrey, Av. Eugenio Garza Sada 2501, Col. Tecnológico C.P. Monterrey, Nuevo León, 64700, Mexico., Kim H; School of Mechanical Engineering, Korea University, Seoul, 02841, Republic of Korea., Shin SR; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA., Park JU; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea.; Institute of Medical and Biological Engineering, Bio-max Institute, Interdisciplinary Program in Bioengineering, Seoul National University, 08826, Seoul, Republic of Korea.
Source: Bioactive materials [Bioact Mater] 2025 May 26; Vol. 51, pp. 559-574. Date of Electronic Publication: 2025 May 26 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ke Ai Publishing Country of Publication: China NLM ID: 101685294 Publication Model: eCollection Cited Medium: Internet ISSN: 2452-199X (Electronic) Linking ISSN: 2452199X NLM ISO Abbreviation: Bioact Mater Subsets: PubMed not MEDLINE
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  Data: Sustained oxygen-releasing hydrogel implants enhance flap regeneration by promoting mitochondrial biogenesis under mild hypoxia.
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  Data: <searchLink fieldCode="AU" term="%22Jeon+S%22">Jeon S</searchLink>; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea.; Division of Pediatric Plastic Surgery, Seoul National University Children's Hospital, Seoul National University College of Medicine, 03080, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+SH%22">Jeong SH</searchLink>; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea.; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.; Institute of Medical and Biological Engineering, Bio-max Institute, Interdisciplinary Program in Bioengineering, Seoul National University, 08826, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MH%22">Lee MH</searchLink>; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Seo+JW%22">Seo JW</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Kim+DS%22">Kim DS</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Bassous+NJ%22">Bassous NJ</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Lozano+Soto+JA%22">Lozano Soto JA</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Choi+C%22">Choi C</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez+ML%22">Gonzalez ML</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Nolasco+Díaz+EB%22">Nolasco Díaz EB</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.; Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Campus Monterrey, Av. Eugenio Garza Sada 2501, Col. Tecnológico C.P. Monterrey, Nuevo León, 64700, Mexico.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; School of Mechanical Engineering, Korea University, Seoul, 02841, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+SR%22">Shin SR</searchLink>; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Park+JU%22">Park JU</searchLink>; Department of Plastic and Reconstructive Surgery, Seoul National University Boramae Hospital, Seoul National University College of Medicine, 07061, Seoul, Republic of Korea.; Institute of Medical and Biological Engineering, Bio-max Institute, Interdisciplinary Program in Bioengineering, Seoul National University, 08826, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101685294%22">Bioactive materials</searchLink> [Bioact Mater] 2025 May 26; Vol. 51, pp. 559-574. <i>Date of Electronic Publication: </i>2025 May 26 (<i>Print Publication: </i>2025).
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