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Analytical validation of Aspyre Clinical Test for Lung (Blood): A multiplexed PCR and pyrophosphorolysis-based assay for detecting actionable NSCLC variants in plasma cfDNA and cfRNA.

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Title: Analytical validation of Aspyre Clinical Test for Lung (Blood): A multiplexed PCR and pyrophosphorolysis-based assay for detecting actionable NSCLC variants in plasma cfDNA and cfRNA.
Authors: Evans RT; Biofidelity Inc., Morrisville, NC, USA., Knudsen KE; Biofidelity Inc., Morrisville, NC, USA., Gillon-Zhang E; Biofidelity Inc., Morrisville, NC, USA., Brown JN; Biofidelity Inc., Morrisville, NC, USA., King C; Biofidelity Inc., Morrisville, NC, USA., Rossi MB; Biofidelity Inc., Morrisville, NC, USA., Kiser C; Biofidelity Inc., Morrisville, NC, USA., Schaffernoth JA; Biofidelity Inc., Morrisville, NC, USA., Green AS; Biofidelity Inc., Morrisville, NC, USA., Silva AL; Biofidelity Ltd., Cambridge, United Kingdom., von Bargen K; Biofidelity Ltd., Cambridge, United Kingdom., Mordaka JM; Biofidelity Ltd., Cambridge, United Kingdom., Palmer RN; Biofidelity Ltd., Cambridge, United Kingdom., Tomassini A; Biofidelity Ltd., Cambridge, United Kingdom., Collazos A; Biofidelity Ltd., Cambridge, United Kingdom., Andreazza S; Biofidelity Ltd., Cambridge, United Kingdom., Turner I; Biofidelity Ltd., Cambridge, United Kingdom., Ho CH; Biofidelity Ltd., Cambridge, United Kingdom., Nugent D; Biofidelity Ltd., Cambridge, United Kingdom., Jose J; Biofidelity Ltd., Cambridge, United Kingdom., Xyrafaki C; Biofidelity Inc., Morrisville, NC, USA., Barot P; Biofidelity Ltd., Cambridge, United Kingdom., Stolarek-Januszkiewicz M; Biofidelity Ltd., Cambridge, United Kingdom., Abujudeh S; Biofidelity Ltd., Cambridge, United Kingdom., Gray ER; Biofidelity Ltd., Cambridge, United Kingdom., Gregg J; Biofidelity Inc., Morrisville, NC, USA., Levin WJ; Biofidelity Inc., Morrisville, NC, USA., Balmforth BW; Biofidelity Ltd., Cambridge, United Kingdom., Pitts K; Biofidelity Inc., Morrisville, NC, USA., Brown S; Biofidelity Inc., Morrisville, NC, USA.
Source: The journal of liquid biopsy [J Liq Biopsy] 2025 May 15; Vol. 8, pp. 100298. Date of Electronic Publication: 2025 May 15 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: United States NLM ID: 9918957761506676 Publication Model: eCollection Cited Medium: Internet ISSN: 2950-1954 (Electronic) Linking ISSN: 29501954 NLM ISO Abbreviation: J Liq Biopsy Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: <searchLink fieldCode="AU" term="%22Evans+RT%22">Evans RT</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Knudsen+KE%22">Knudsen KE</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gillon-Zhang+E%22">Gillon-Zhang E</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Brown+JN%22">Brown JN</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22King+C%22">King C</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Rossi+MB%22">Rossi MB</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kiser+C%22">Kiser C</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Schaffernoth+JA%22">Schaffernoth JA</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Green+AS%22">Green AS</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Silva+AL%22">Silva AL</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22von+Bargen+K%22">von Bargen K</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mordaka+JM%22">Mordaka JM</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Palmer+RN%22">Palmer RN</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tomassini+A%22">Tomassini A</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Collazos+A%22">Collazos A</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Andreazza+S%22">Andreazza S</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Turner+I%22">Turner I</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ho+CH%22">Ho CH</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nugent+D%22">Nugent D</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jose+J%22">Jose J</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Xyrafaki+C%22">Xyrafaki C</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Barot+P%22">Barot P</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Stolarek-Januszkiewicz+M%22">Stolarek-Januszkiewicz M</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Abujudeh+S%22">Abujudeh S</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gray+ER%22">Gray ER</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gregg+J%22">Gregg J</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Levin+WJ%22">Levin WJ</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Balmforth+BW%22">Balmforth BW</searchLink>; Biofidelity Ltd., Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pitts+K%22">Pitts K</searchLink>; Biofidelity Inc., Morrisville, NC, USA.<br /><searchLink fieldCode="AU" term="%22Brown+S%22">Brown S</searchLink>; Biofidelity Inc., Morrisville, NC, USA.
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  Data: <searchLink fieldCode="JN" term="%229918957761506676%22">The journal of liquid biopsy</searchLink> [J Liq Biopsy] 2025 May 15; Vol. 8, pp. 100298. <i>Date of Electronic Publication: </i>2025 May 15 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918957761506676 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2950-1954 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2229501954%22">29501954 </searchLink><i>NLM ISO Abbreviation: </i>J Liq Biopsy <i>Subsets: </i>PubMed not MEDLINE
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