Disassembly activates Retron-Septu for antiphage defense.

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Title: Disassembly activates Retron-Septu for antiphage defense.
Authors: Wang C; Department of Pathology, UMass Chan Medical School, Worcester, MA, USA.; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, USA.; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA.; Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH, USA., Rish AD; Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH, USA., Armbruster EG; School of Biological Sciences, University of California, San Diego, San Diego, CA, USA., Xie J; Department of Pathology, UMass Chan Medical School, Worcester, MA, USA.; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, USA.; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA., Loveland AB; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, USA., Shen Z; Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH, USA., Gu B; Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH, USA.; Coffman High School, Dublin, OH, USA., Korostelev AA; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, USA., Pogliano J; School of Biological Sciences, University of California, San Diego, San Diego, CA, USA., Fu TM; Department of Pathology, UMass Chan Medical School, Worcester, MA, USA.; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, USA.; Department of Biochemistry and Molecular Biotechnology, UMass Chan Medical School, Worcester, MA, USA.; Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH, USA.
Source: Science (New York, N.Y.) [Science] 2025 Aug 21; Vol. 389 (6762), pp. eadv3344. Date of Electronic Publication: 2025 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-9203
DOI:10.1126/science.adv3344