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A peptide vaccine targeting the CMV antigen pp65 in children and young adults with recurrent high-grade glioma and medulloblastoma: a phase 1 trial.

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Title: A peptide vaccine targeting the CMV antigen pp65 in children and young adults with recurrent high-grade glioma and medulloblastoma: a phase 1 trial.
Authors: Thompson EM; Department of Neurological Surgery, Duke University, Durham, NC, USA. t.eric@wustl.edu.; Department of Neurological Surgery, The University of Chicago, Chicago, IL, USA. t.eric@wustl.edu.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA. t.eric@wustl.edu.; Department of Neurological Surgery, Washington University, St. Louis, MO, USA. t.eric@wustl.edu., Ashley DM; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Ayasoufi K; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Norberg P; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Archer G; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Buckley ED; Duke Cancer Institute Biostatistics, Duke University, Durham, NC, USA., Herndon JE 2nd; Department of Biostatistics and Bioinformatics, Duke University, Durham, NC, USA., Walter A; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Archambault B; Department of Pediatrics, Duke University, Durham, NC, USA., Flahiff C; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Jaggers D; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Gorski L; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Sanchez LA; Department of Neurological Surgery, Duke University, Durham, NC, USA., Congdon K; Department of Neurological Surgery, Duke University, Durham, NC, USA., Hotchkiss K; Department of Neurological Surgery, Duke University, Durham, NC, USA., Cook SL; Department of Neurological Surgery, Duke University, Durham, NC, USA., Moelker E; Department of Neurological Surgery, Duke University, Durham, NC, USA., Vlahovic G; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Reap E; Department of Neurological Surgery, Duke University, Durham, NC, USA., Schroeder K; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA.; Department of Pediatrics, Duke University, Durham, NC, USA., Randazzo D; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Desjardins A; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Johnson MO; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Peters K; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Khasraw M; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Friedman H; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Mitchell DA; Department of Neurological Surgery, The University of Florida, Gainesville, FL, USA., Sampson JH; Department of Neurological Surgery, Duke University, Durham, NC, USA.; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA., Landi D; Preston Robert Tisch Brain Tumor Center, Duke University, Durham, NC, USA.; Department of Pediatrics, Duke University, Durham, NC, USA.
Source: Nature cancer [Nat Cancer] 2025 Sep; Vol. 6 (9), pp. 1559-1569. Date of Electronic Publication: 2025 Jun 12.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
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