Patient-derived organotypic tumor spheroids, tumoroids, and organoids: advancing immunotherapy using state-of-the-art 3D tumor model systems.

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Title: Patient-derived organotypic tumor spheroids, tumoroids, and organoids: advancing immunotherapy using state-of-the-art 3D tumor model systems.
Authors: Bozym DJ; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu., Zheng DX; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Revach OY; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Aref A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Gastrointestinal and Oncologic Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA., Jenkins RW; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Source: Lab on a chip [Lab Chip] 2025 Jun 24; Vol. 25 (13), pp. 3038-3059. Date of Electronic Publication: 2025 Jun 24.
Publication Type: Journal Article; Review
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101128948 Publication Model: Electronic Cited Medium: Internet ISSN: 1473-0189 (Electronic) Linking ISSN: 14730189 NLM ISO Abbreviation: Lab Chip Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Bozym+DJ%22">Bozym DJ</searchLink>; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Zheng+DX%22">Zheng DX</searchLink>; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Revach+OY%22">Revach OY</searchLink>; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Aref+A%22">Aref A</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Gastrointestinal and Oncologic Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jenkins+RW%22">Jenkins RW</searchLink>; Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Jackson 904B, Boston, MA 02114, USA. rjenkins@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101128948%22">Lab on a chip</searchLink> [Lab Chip] 2025 Jun 24; Vol. 25 (13), pp. 3038-3059. <i>Date of Electronic Publication: </i>2025 Jun 24.
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      – Type: doi
        Value: 10.1039/d5lc00062a
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      – Code: eng
        Text: English
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        StartPage: 3038
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      – TitleFull: Patient-derived organotypic tumor spheroids, tumoroids, and organoids: advancing immunotherapy using state-of-the-art 3D tumor model systems.
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            NameFull: Bozym DJ
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              Text: 2025 Jun 24
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