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Sexually Dimorphic Responses Reveal Multifaceted Benefits of Glibenclamide in Traumatic Brain Injury.

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Title: Sexually Dimorphic Responses Reveal Multifaceted Benefits of Glibenclamide in Traumatic Brain Injury.
Authors: Rani A; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Raikwar SP; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Yoo W; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.; Ivy Brain Tumor Center and Department of Translational Neuroscience, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Ahmad S; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Vagni VA; Department of Critical Care Medicine, Pittsburgh, Pennsylvania, USA.; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Janesko-Feldman KL; Department of Critical Care Medicine, Pittsburgh, Pennsylvania, USA.; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Carlson SW; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Eberle A; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Miller M; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Helm J; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Catapano J; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Zusman BE; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Desai S; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Javelosa RAM; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Afework S; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., McNally EA; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Kohanbash G; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Pediatrics, Pittsburgh, Pennsylvania, USA., Rajasundaram D; Department of Pediatrics, Pittsburgh, Pennsylvania, USA.; Division of Health Informatics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Waters MF; Division of Vascular Neurology, Mount Sinai Health System, New York, USA., Ducruet A; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Jadhav A; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Kumar A; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Phuah CL; Department of Neurology, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA., Kochanek PM; Department of Critical Care Medicine, Pittsburgh, Pennsylvania, USA.; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Pediatrics, Pittsburgh, Pennsylvania, USA.; UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA., Jha RM; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.; Department of Neurology, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Source: Journal of neurotrauma [J Neurotrauma] 2025 Aug; Vol. 42 (15-16), pp. 1319-1344. Date of Electronic Publication: 2025 Jun 12.
Publication Type: Journal Article
Journal Info: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 8811626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-9042 (Electronic) Linking ISSN: 08977151 NLM ISO Abbreviation: J Neurotrauma Subsets: MEDLINE
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  Data: Sexually Dimorphic Responses Reveal Multifaceted Benefits of Glibenclamide in Traumatic Brain Injury.
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  Data: <searchLink fieldCode="AU" term="%22Rani+A%22">Rani A</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Raikwar+SP%22">Raikwar SP</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Yoo+W%22">Yoo W</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.; Ivy Brain Tumor Center and Department of Translational Neuroscience, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Ahmad+S%22">Ahmad S</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Vagni+VA%22">Vagni VA</searchLink>; Department of Critical Care Medicine, Pittsburgh, Pennsylvania, USA.; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Janesko-Feldman+KL%22">Janesko-Feldman KL</searchLink>; Department of Critical Care Medicine, Pittsburgh, Pennsylvania, USA.; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Carlson+SW%22">Carlson SW</searchLink>; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Eberle+A%22">Eberle A</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Miller+M%22">Miller M</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Helm+J%22">Helm J</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Catapano+J%22">Catapano J</searchLink>; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Zusman+BE%22">Zusman BE</searchLink>; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Desai+S%22">Desai S</searchLink>; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Javelosa+RAM%22">Javelosa RAM</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Afework+S%22">Afework S</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22McNally+EA%22">McNally EA</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Kohanbash+G%22">Kohanbash G</searchLink>; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Pediatrics, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Rajasundaram+D%22">Rajasundaram D</searchLink>; Department of Pediatrics, Pittsburgh, Pennsylvania, USA.; Division of Health Informatics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Waters+MF%22">Waters MF</searchLink>; Division of Vascular Neurology, Mount Sinai Health System, New York, USA.<br /><searchLink fieldCode="AU" term="%22Ducruet+A%22">Ducruet A</searchLink>; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Jadhav+A%22">Jadhav A</searchLink>; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+A%22">Kumar A</searchLink>; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Phuah+CL%22">Phuah CL</searchLink>; Department of Neurology, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Kochanek+PM%22">Kochanek PM</searchLink>; Department of Critical Care Medicine, Pittsburgh, Pennsylvania, USA.; Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Pediatrics, Pittsburgh, Pennsylvania, USA.; UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Jha+RM%22">Jha RM</searchLink>; Department of Translational Neuroscience, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.; Department of Neurosurgery, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.; Department of Neurology, Barrow Neurological Institute and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
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  Data: <searchLink fieldCode="JN" term="%228811626%22">Journal of neurotrauma</searchLink> [J Neurotrauma] 2025 Aug; Vol. 42 (15-16), pp. 1319-1344. <i>Date of Electronic Publication: </i>2025 Jun 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mary+Ann+Liebert%22">Mary Ann Liebert </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8811626 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-9042 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208977151%22">08977151 </searchLink><i>NLM ISO Abbreviation: </i>J Neurotrauma <i>Subsets: </i>MEDLINE
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