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Aptamer-targeted anti-miR RNA construct based on 3WJ as a new approach for the treatment of chronic kidney disease in an experimental model.

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Title: Aptamer-targeted anti-miR RNA construct based on 3WJ as a new approach for the treatment of chronic kidney disease in an experimental model.
Authors: Alsenousy AHA; Department of Biochemistry, Medical Research Institute, University of Alexandria, Alexandria, Egypt. aisha.ali@alexu.edu.eg., Sharker SA; Department of Biochemistry, Medical Research Institute, University of Alexandria, Alexandria, Egypt., Gowayed MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt., Elblehi SS; Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt., Kamel MA; Department of Biochemistry, Medical Research Institute, University of Alexandria, Alexandria, Egypt.; Research Projects unit, Pharos University in Alexandria, 21648, Alexandria, Egypt.
Source: Gene therapy [Gene Ther] 2025 Jul; Vol. 32 (4), pp. 359-375. Date of Electronic Publication: 2025 Jun 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Alsenousy+AHA%22">Alsenousy AHA</searchLink>; Department of Biochemistry, Medical Research Institute, University of Alexandria, Alexandria, Egypt. aisha.ali@alexu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Sharker+SA%22">Sharker SA</searchLink>; Department of Biochemistry, Medical Research Institute, University of Alexandria, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Gowayed+MA%22">Gowayed MA</searchLink>; Department of Pharmacology and Therapeutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Elblehi+SS%22">Elblehi SS</searchLink>; Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Kamel+MA%22">Kamel MA</searchLink>; Department of Biochemistry, Medical Research Institute, University of Alexandria, Alexandria, Egypt.; Research Projects unit, Pharos University in Alexandria, 21648, Alexandria, Egypt.
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  Data: <searchLink fieldCode="JN" term="%229421525%22">Gene therapy</searchLink> [Gene Ther] 2025 Jul; Vol. 32 (4), pp. 359-375. <i>Date of Electronic Publication: </i>2025 Jun 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9421525 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5462 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209697128%22">09697128 </searchLink><i>NLM ISO Abbreviation: </i>Gene Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41434-025-00544-7
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        Text: English
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              Text: 2025 Jul
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