Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model.
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| Title: | Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model. |
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| Authors: | Schumacher J; Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infections, University of Tübingen, Tübingen, Germany.; Environmental Biotechnology Group, Department of Geosciences, University of Tübingen, Tübingen, Germany., Müller P; Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infections, University of Tübingen, Tübingen, Germany.; Interfaculty Institute for Microbiology and Infection Medicine Tübingen, University of Tübingen, Tübingen, Germany.; M3-Research Center for Malignome, Metabolome and Microbiome, University of Tübingen, Tübingen, Germany., Sulzer J; Helmholtz Centre for Infection Research, Helmholtz Institute for RNA-based Infection Research (HIRI) Würzburg, Würzburg, Germany.; Institute for Hygiene and Microbiology, Julius-Maximilians-University of Würzburg, Würzburg, Germany., Faber F; Helmholtz Centre for Infection Research, Helmholtz Institute for RNA-based Infection Research (HIRI) Würzburg, Würzburg, Germany.; Institute for Hygiene and Microbiology, Julius-Maximilians-University of Würzburg, Würzburg, Germany., Molitor B; Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infections, University of Tübingen, Tübingen, Germany.; Environmental Biotechnology Group, Department of Geosciences, University of Tübingen, Tübingen, Germany., Maier L; Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infections, University of Tübingen, Tübingen, Germany.; Interfaculty Institute for Microbiology and Infection Medicine Tübingen, University of Tübingen, Tübingen, Germany.; M3-Research Center for Malignome, Metabolome and Microbiome, University of Tübingen, Tübingen, Germany. |
| Source: | Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2519697. Date of Electronic Publication: 2025 Jun 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1949-0984 |
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| DOI: | 10.1080/19490976.2025.2519697 |
