Identification of HIF1A as a therapeutic target during SARS-CoV-2-associated lung injury.
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| Title: | Identification of HIF1A as a therapeutic target during SARS-CoV-2-associated lung injury. |
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| Authors: | Bobrow B; Department of Emergency Medicine, McGovern Medical School., Luber SD; Department of Emergency Medicine, McGovern Medical School., Potnuru P; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Figarella K; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Kim J; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Wang Y; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Bang IH; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Robinson D; Department of Emergency Medicine, McGovern Medical School., Sergot PB; Department of Emergency Medicine, McGovern Medical School., Burke SK; Akebia Therapeutics, Inc., Cambridge, Massachusetts, USA., Mills T; Department of Biochemistry, McGovern Medical School, and., de Dios C; Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Suchting R; Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Williams GW; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Ginde AA; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA., Liang Y; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Liu H; Department of Health Data Science and Artificial Intelligence, D. Bradley McWilliams School of Biomedical Informatics, and., Green C; Institute for Clinical Research and Learning Health Care, Department of Pediatrics, UTHealth Houston; Houston, Texas, USA., Doursout MF; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Turan A; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Sessler DI; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA., Yuan X; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and., Eltzschig HK; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA. |
| Source: | JCI insight [JCI Insight] 2025 Jun 17; Vol. 10 (14). Date of Electronic Publication: 2025 Jun 17 (Print Publication: 2025). |
| Publication Type: | Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40526427 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Identification of HIF1A as a therapeutic target during SARS-CoV-2-associated lung injury. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bobrow+B%22">Bobrow B</searchLink>; Department of Emergency Medicine, McGovern Medical School.<br /><searchLink fieldCode="AU" term="%22Luber+SD%22">Luber SD</searchLink>; Department of Emergency Medicine, McGovern Medical School.<br /><searchLink fieldCode="AU" term="%22Potnuru+P%22">Potnuru P</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Figarella+K%22">Figarella K</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Bang+IH%22">Bang IH</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Robinson+D%22">Robinson D</searchLink>; Department of Emergency Medicine, McGovern Medical School.<br /><searchLink fieldCode="AU" term="%22Sergot+PB%22">Sergot PB</searchLink>; Department of Emergency Medicine, McGovern Medical School.<br /><searchLink fieldCode="AU" term="%22Burke+SK%22">Burke SK</searchLink>; Akebia Therapeutics, Inc., Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Mills+T%22">Mills T</searchLink>; Department of Biochemistry, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22de+Dios+C%22">de Dios C</searchLink>; Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Suchting+R%22">Suchting R</searchLink>; Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Williams+GW%22">Williams GW</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Ginde+AA%22">Ginde AA</searchLink>; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Health Data Science and Artificial Intelligence, D. Bradley McWilliams School of Biomedical Informatics, and.<br /><searchLink fieldCode="AU" term="%22Green+C%22">Green C</searchLink>; Institute for Clinical Research and Learning Health Care, Department of Pediatrics, UTHealth Houston; Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Doursout+MF%22">Doursout MF</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Turan+A%22">Turan A</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Sessler+DI%22">Sessler DI</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+X%22">Yuan X</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.<br /><searchLink fieldCode="AU" term="%22Eltzschig+HK%22">Eltzschig HK</searchLink>; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, and.; Center for Outcomes Research, Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2025 Jun 17; Vol. 10 (14). <i>Date of Electronic Publication: </i>2025 Jun 17 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676073 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2379-3708 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223793708%22">23793708 </searchLink><i>NLM ISO Abbreviation: </i>JCI Insight <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40526427 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1172/jci.insight.191463 Languages: – Code: eng Text: English Titles: – TitleFull: Identification of HIF1A as a therapeutic target during SARS-CoV-2-associated lung injury. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bobrow B – PersonEntity: Name: NameFull: Luber SD – PersonEntity: Name: NameFull: Potnuru P – PersonEntity: Name: NameFull: Figarella K – PersonEntity: Name: NameFull: Kim J – PersonEntity: Name: NameFull: Wang Y – PersonEntity: Name: NameFull: Bang IH – PersonEntity: Name: NameFull: Robinson D – PersonEntity: Name: NameFull: Sergot PB – PersonEntity: Name: NameFull: Burke SK – PersonEntity: Name: NameFull: Mills T – PersonEntity: Name: NameFull: de Dios C – PersonEntity: Name: NameFull: Suchting R – PersonEntity: Name: NameFull: Williams GW – PersonEntity: Name: NameFull: Ginde AA – PersonEntity: Name: NameFull: Liang Y – PersonEntity: Name: NameFull: Liu H – PersonEntity: Name: NameFull: Green C – PersonEntity: Name: NameFull: Doursout MF – PersonEntity: Name: NameFull: Turan A – PersonEntity: Name: NameFull: Sessler DI – PersonEntity: Name: NameFull: Yuan X – PersonEntity: Name: NameFull: Eltzschig HK IsPartOfRelationships: – BibEntity: Dates: – D: 17 M: 06 Text: 2025 Jun 17 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2379-3708 Numbering: – Type: volume Value: 10 – Type: issue Value: 14 Titles: – TitleFull: JCI insight Type: main |
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