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Allergens abrogate antiinflammatory DNA effects and unmask macrophage-driven neutrophilic asthma via ILC2/STING/TNF-α signaling.

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Title: Allergens abrogate antiinflammatory DNA effects and unmask macrophage-driven neutrophilic asthma via ILC2/STING/TNF-α signaling.
Authors: Sripada A; Division of Allergy & Immunology., Verma D; Division of Allergy & Immunology., Varma R; Division of Allergy & Immunology., Sirohi K; Division of Allergy & Immunology., Kwiat C; Division of Allergy & Immunology., Pathria M; Division of Allergy & Immunology., Verma M; Division of Allergy & Immunology., Sahu A; Division of Allergy & Immunology., Guntur V; Division of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colorado, USA.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA., Manka L; Division of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colorado, USA.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA., Vestal B; Department of Immunology & Genomic Medicine, National Jewish Health, Denver, Colorado, USA., Moore C; Department of Immunology & Genomic Medicine, National Jewish Health, Denver, Colorado, USA., Martin RJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colorado, USA., Gorska MM; Division of Allergy & Immunology.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA., Cambier J; Department of Immunology and Microbiology, University of Colorado Denver, School of Medicine, Denver, Colorado, USA., Getahun A; Department of Immunology and Microbiology, University of Colorado Denver, School of Medicine, Denver, Colorado, USA., Alam R; Division of Allergy & Immunology.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Jun 17; Vol. 135 (16). Date of Electronic Publication: 2025 Jun 17 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Allergens abrogate antiinflammatory DNA effects and unmask macrophage-driven neutrophilic asthma via ILC2/STING/TNF-α signaling.
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  Data: <searchLink fieldCode="AU" term="%22Sripada+A%22">Sripada A</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Verma+D%22">Verma D</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Varma+R%22">Varma R</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Sirohi+K%22">Sirohi K</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Kwiat+C%22">Kwiat C</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Pathria+M%22">Pathria M</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Verma+M%22">Verma M</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Sahu+A%22">Sahu A</searchLink>; Division of Allergy & Immunology.<br /><searchLink fieldCode="AU" term="%22Guntur+V%22">Guntur V</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colorado, USA.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Manka+L%22">Manka L</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colorado, USA.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Vestal+B%22">Vestal B</searchLink>; Department of Immunology & Genomic Medicine, National Jewish Health, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Moore+C%22">Moore C</searchLink>; Department of Immunology & Genomic Medicine, National Jewish Health, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Martin+RJ%22">Martin RJ</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, National Jewish Health, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Gorska+MM%22">Gorska MM</searchLink>; Division of Allergy & Immunology.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Cambier+J%22">Cambier J</searchLink>; Department of Immunology and Microbiology, University of Colorado Denver, School of Medicine, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Getahun+A%22">Getahun A</searchLink>; Department of Immunology and Microbiology, University of Colorado Denver, School of Medicine, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Alam+R%22">Alam R</searchLink>; Division of Allergy & Immunology.; Department of Medicine, University of Colorado Denver, School of Medicine, Denver, Colorado, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Jun 17; Vol. 135 (16). <i>Date of Electronic Publication: </i>2025 Jun 17 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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        Value: 10.1172/JCI187907
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              Text: 2025 Jun 17
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