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Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation.

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Title: Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation.
Authors: Gutjahr JC; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Department of Biology, University of Konstanz, Konstanz 78464, Germany., Hub E; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Center for Translational Medicine and Therapeutics, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Anderson CA; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Samus M; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Artinger K; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz 8036, Austria., Gomez EA; Biochemical Pharmacology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Ratswohl C; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Department of Biology, University of Konstanz, Konstanz 78464, Germany., Wickli N; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern 3012, Switzerland., Raum M; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern 3012, Switzerland., Dufton N; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Dalli J; Biochemical Pharmacology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Burden JJ; Laboratory for Molecular Cell Biology, University College London, London, WC1E 6BT, UK., Duchene J; Institute for Cardiovascular Prevention, Ludwig-Maximilians University, Munich 80336, Germany., Rot A; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Center for Translational Medicine and Therapeutics, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
Source: Science signaling [Sci Signal] 2025 Jun 17; Vol. 18 (891), pp. eadt2678. Date of Electronic Publication: 2025 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation.
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  Data: <searchLink fieldCode="AU" term="%22Gutjahr+JC%22">Gutjahr JC</searchLink>; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Department of Biology, University of Konstanz, Konstanz 78464, Germany.<br /><searchLink fieldCode="AU" term="%22Hub+E%22">Hub E</searchLink>; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Center for Translational Medicine and Therapeutics, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Anderson+CA%22">Anderson CA</searchLink>; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Samus+M%22">Samus M</searchLink>; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Artinger+K%22">Artinger K</searchLink>; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz 8036, Austria.<br /><searchLink fieldCode="AU" term="%22Gomez+EA%22">Gomez EA</searchLink>; Biochemical Pharmacology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Ratswohl+C%22">Ratswohl C</searchLink>; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Department of Biology, University of Konstanz, Konstanz 78464, Germany.<br /><searchLink fieldCode="AU" term="%22Wickli+N%22">Wickli N</searchLink>; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern 3012, Switzerland.<br /><searchLink fieldCode="AU" term="%22Raum+M%22">Raum M</searchLink>; Institute of Cell Biology and Immunology Thurgau (BITG), University of Konstanz, Kreuzlingen 8280, Switzerland.; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern 3012, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dufton+N%22">Dufton N</searchLink>; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Dalli+J%22">Dalli J</searchLink>; Biochemical Pharmacology, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Burden+JJ%22">Burden JJ</searchLink>; Laboratory for Molecular Cell Biology, University College London, London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Duchene+J%22">Duchene J</searchLink>; Institute for Cardiovascular Prevention, Ludwig-Maximilians University, Munich 80336, Germany.<br /><searchLink fieldCode="AU" term="%22Rot+A%22">Rot A</searchLink>; Centre for Microvascular Research, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Center for Translational Medicine and Therapeutics, William Harvey Research Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
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