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Sedation and analgesia in post-cardiac arrest care: a post hoc analysis of the TTM2 trial.

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Title: Sedation and analgesia in post-cardiac arrest care: a post hoc analysis of the TTM2 trial.
Authors: Ceric A; Anesthesia & Intensive Care, Department of Clinical Sciences, Lund University, Skane University Hospital, Carl Bertil Laurels Gata 9, 214 28, Malmö, Sweden. ameldina.ceric@med.lu.se., Dankiewicz J; Cardiology Department, Lund University, Skåne University Hospital Lund, Lund, Sweden., Cronberg T; Neurology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden., Düring J; Department of Clinical Sciences, Anaesthesia and Intensive Care, Lund University, Skåne University Hospital, Malmö, Sweden., Moseby-Knappe M; Department of Clinical Sciences Lund, Neurology and Rehabilitation, Lund University, Lund, Sweden., Annborn M; Department of Clinical Sciences, Anaesthesia and Intensive Care, Lund University, Helsingborg Hospital, Helsingborg, Sweden., May TL; Department of Critical Care, Maine Medical Center, Portland, ME, USA., Thomas M; Department of Intensive Care, University Hospitals Bristol and Weston, Bristol, UK., Grejs AM; Department of Intensive Care Medicine, Aarhus University Hospital, Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark., Rylander C; Anaesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University and Uppsala University Hospital, Uppsala, Sweden., Belohlavek J; 2Nd Department of Internal Mediciny, Cardiovascular Medicine, General University Hospital, and 1St Medical School in Prague, Prague, Czech Republic.; Institute of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland., Wendel-Garcia P; Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland., Haenggi M; Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.; Department of Intensive Care Medicine, University Hospital Bern, University of Bern, Bern, Switzerland., Schrag C; Intensive Care Department, Kantonsspital St. Gallen, St. Gallen, Switzerland., Hilty MP; Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland., Keeble TR; Anglia Ruskin School of Medicine, Essex Cardiothoracic Centre, MSE NHS Trust, Essex, UK. MTRC, Chelmsford, Essex, UK., Wise MP; Adult Critical Care, University Hospital of Wales, Cardiff, UK., Young P; Intensive Care Unit, Wellington Hospital, Wellington, New Zealand and Medical Research Institute of New Zealand, Wellington, New Zealand., Taccone FS; Department of Intensive Care, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, Brussels, Belgium., Robba C; IRCCS Policlinico San Martino; Genoa, Italy and Dipartimento Di Scienze Chirurgiche Diagnostiche E Integrate, University of Genoa, Genoa, Italy., Cariou A; Medical ICU Cochin University Hospital, AP-HP Centre Université Paris Cité, Paris, France., Eastwood G; The Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia., Saxena M; Division of Critical Care and Trauma, George Institute for Global Health, and Bankstown-Lidcombe Hospital, South Western Sydney Local Health District, Sydney, Australia., Ullén S; Skåne University Hospital Lund, Lund University and Clinical Studies Sweden - Forum South, Skåne University Hospital, Lund, Sweden., Lilja G; Neurology Department of Clinical Sciences, Lund University, Lund, Sweden., Jakobsen JC; Copenhagen Trial Unit - Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; The Faculty of Health Sciences, Department of Regional Health Research, University of Southern Denmark, Odense M, Denmark., Lybeck A; Department of Clinical Sciences, Anaesthesia and Intensive Care, Skåne University Hospital, Lund University, Lund, Sweden., Nielsen N; Department of Clinical Sciences, Anaesthesia and Intensive Care, Lund University, Helsingborg Hospital, Helsingborg, Sweden.
Source: Critical care (London, England) [Crit Care] 2025 Jun 17; Vol. 29 (1), pp. 247. Date of Electronic Publication: 2025 Jun 17.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ceric+A%22">Ceric A</searchLink>; Anesthesia & Intensive Care, Department of Clinical Sciences, Lund University, Skane University Hospital, Carl Bertil Laurels Gata 9, 214 28, Malmö, Sweden. ameldina.ceric@med.lu.se.<br /><searchLink fieldCode="AU" term="%22Dankiewicz+J%22">Dankiewicz J</searchLink>; Cardiology Department, Lund University, Skåne University Hospital Lund, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Cronberg+T%22">Cronberg T</searchLink>; Neurology, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Düring+J%22">Düring J</searchLink>; Department of Clinical Sciences, Anaesthesia and Intensive Care, Lund University, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Moseby-Knappe+M%22">Moseby-Knappe M</searchLink>; Department of Clinical Sciences Lund, Neurology and Rehabilitation, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Annborn+M%22">Annborn M</searchLink>; Department of Clinical Sciences, Anaesthesia and Intensive Care, Lund University, Helsingborg Hospital, Helsingborg, Sweden.<br /><searchLink fieldCode="AU" term="%22May+TL%22">May TL</searchLink>; Department of Critical Care, Maine Medical Center, Portland, ME, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+M%22">Thomas M</searchLink>; Department of Intensive Care, University Hospitals Bristol and Weston, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Grejs+AM%22">Grejs AM</searchLink>; Department of Intensive Care Medicine, Aarhus University Hospital, Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.<br /><searchLink fieldCode="AU" term="%22Rylander+C%22">Rylander C</searchLink>; Anaesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University and Uppsala University Hospital, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Belohlavek+J%22">Belohlavek J</searchLink>; 2Nd Department of Internal Mediciny, Cardiovascular Medicine, General University Hospital, and 1St Medical School in Prague, Prague, Czech Republic.; Institute of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Wendel-Garcia+P%22">Wendel-Garcia P</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Haenggi+M%22">Haenggi M</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.; Department of Intensive Care Medicine, University Hospital Bern, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schrag+C%22">Schrag C</searchLink>; Intensive Care Department, Kantonsspital St. Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hilty+MP%22">Hilty MP</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Keeble+TR%22">Keeble TR</searchLink>; Anglia Ruskin School of Medicine, Essex Cardiothoracic Centre, MSE NHS Trust, Essex, UK. MTRC, Chelmsford, Essex, UK.<br /><searchLink fieldCode="AU" term="%22Wise+MP%22">Wise MP</searchLink>; Adult Critical Care, University Hospital of Wales, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Young+P%22">Young P</searchLink>; Intensive Care Unit, Wellington Hospital, Wellington, New Zealand and Medical Research Institute of New Zealand, Wellington, New Zealand.<br /><searchLink fieldCode="AU" term="%22Taccone+FS%22">Taccone FS</searchLink>; Department of Intensive Care, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Robba+C%22">Robba C</searchLink>; IRCCS Policlinico San Martino; Genoa, Italy and Dipartimento Di Scienze Chirurgiche Diagnostiche E Integrate, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Cariou+A%22">Cariou A</searchLink>; Medical ICU Cochin University Hospital, AP-HP Centre Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Eastwood+G%22">Eastwood G</searchLink>; The Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Saxena+M%22">Saxena M</searchLink>; Division of Critical Care and Trauma, George Institute for Global Health, and Bankstown-Lidcombe Hospital, South Western Sydney Local Health District, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Ullén+S%22">Ullén S</searchLink>; Skåne University Hospital Lund, Lund University and Clinical Studies Sweden - Forum South, Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Lilja+G%22">Lilja G</searchLink>; Neurology Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Jakobsen+JC%22">Jakobsen JC</searchLink>; Copenhagen Trial Unit - Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.; The Faculty of Health Sciences, Department of Regional Health Research, University of Southern Denmark, Odense M, Denmark.<br /><searchLink fieldCode="AU" term="%22Lybeck+A%22">Lybeck A</searchLink>; Department of Clinical Sciences, Anaesthesia and Intensive Care, Skåne University Hospital, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Nielsen+N%22">Nielsen N</searchLink>; Department of Clinical Sciences, Anaesthesia and Intensive Care, Lund University, Helsingborg Hospital, Helsingborg, Sweden.
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  Data: <searchLink fieldCode="JN" term="%229801902%22">Critical care (London, England)</searchLink> [Crit Care] 2025 Jun 17; Vol. 29 (1), pp. 247. <i>Date of Electronic Publication: </i>2025 Jun 17.
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