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Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat syndrome.

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Title: Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat syndrome.
Authors: Yang Y; College of Pharmaceutical Science, Soochow University, Suzhou, China., Guo L; Jiangsu Province Engineering Research Center of Molecular Target Therapy and Companion Diagnostics in Oncology, Suzhou Vocational Health College, Suzhou, China., Yu J; College of Pharmaceutical Science, Soochow University, Suzhou, China., Peng W; Department of the Gastrointestinal Surgery, Second Affiliated Hospital of Soochow University, Suzhou, China., Wang Q; Jiangsu Province Engineering Research Center of Molecular Target Therapy and Companion Diagnostics in Oncology, Suzhou Vocational Health College, Suzhou, China., Wei L; College of Pharmaceutical Science, Soochow University, Suzhou, China., Chen X; College of Pharmaceutical Science, Soochow University, Suzhou, China., Min C; Pharmaceutical Standards Laboratory, Suzhou Institute for Drug Control, Suzhou, China., Jiang X; College of Pharmaceutical Science, Soochow University, Suzhou, China., Zhu S; College of Pharmaceutical Science, Soochow University, Suzhou, China., Zhao H; School of International Studies, Shaanxi Normal University, Xian, China., Xuan Z; College of Pharmaceutical Science, Soochow University, Suzhou, China., Yu J; Department of Internal Medicine of Traditional Chinese Medicine, Haian Hospital of Traditional Chinese Medicine, Nantong, China., Zhang J; College of Pharmaceutical Science, Soochow University, Suzhou, China.
Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2519684. Date of Electronic Publication: 2025 Jun 18.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+L%22">Guo L</searchLink>; Jiangsu Province Engineering Research Center of Molecular Target Therapy and Companion Diagnostics in Oncology, Suzhou Vocational Health College, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Peng+W%22">Peng W</searchLink>; Department of the Gastrointestinal Surgery, Second Affiliated Hospital of Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Jiangsu Province Engineering Research Center of Molecular Target Therapy and Companion Diagnostics in Oncology, Suzhou Vocational Health College, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Wei+L%22">Wei L</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Min+C%22">Min C</searchLink>; Pharmaceutical Standards Laboratory, Suzhou Institute for Drug Control, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiang+X%22">Jiang X</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhu+S%22">Zhu S</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; School of International Studies, Shaanxi Normal University, Xian, China.<br /><searchLink fieldCode="AU" term="%22Xuan+Z%22">Xuan Z</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Department of Internal Medicine of Traditional Chinese Medicine, Haian Hospital of Traditional Chinese Medicine, Nantong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; College of Pharmaceutical Science, Soochow University, Suzhou, China.
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  Data: <searchLink fieldCode="JN" term="%228906388%22">Annals of medicine</searchLink> [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2519684. <i>Date of Electronic Publication: </i>2025 Jun 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8906388 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2060 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207853890%22">07853890 </searchLink><i>NLM ISO Abbreviation: </i>Ann Med <i>Subsets: </i>MEDLINE
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        Value: 10.1080/07853890.2025.2519684
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              Text: 2025 Dec
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