Chlorhexidine Gluconate Bathing Has Limited Ability to Prevent Surgical Site Infection Following Operative Fixation of Extremity and Pelvic Fractures.

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Title: Chlorhexidine Gluconate Bathing Has Limited Ability to Prevent Surgical Site Infection Following Operative Fixation of Extremity and Pelvic Fractures.
Authors: Willey MC; Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa., Hebden JN; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland., Herwaldt LA; Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, Iowa., Gaski GE; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia., Kheiri S; Center for Orthopaedics, Injury, and Research Innovation, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland., O'Hara LM; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland., O'Hara NN; Center for Orthopaedics, Injury, and Research Innovation, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland., Sprague S; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Bzovsky S; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada., Gage MJ; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland., Slobogean GP; Center for Orthopaedics, Injury, and Research Innovation, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland.
Corporate Authors: the PREP-IT Investigators
Source: The Journal of bone and joint surgery. American volume [J Bone Joint Surg Am] 2025 Jun 18; Vol. 107 (Suppl 1), pp. 36-42. Date of Electronic Publication: 2025 Jun 18.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Journal of Bone and Joint Surgery Country of Publication: United States NLM ID: 0014030 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-1386 (Electronic) Linking ISSN: 00219355 NLM ISO Abbreviation: J Bone Joint Surg Am Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Chlorhexidine Gluconate Bathing Has Limited Ability to Prevent Surgical Site Infection Following Operative Fixation of Extremity and Pelvic Fractures.
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  Data: <searchLink fieldCode="AU" term="%22Willey+MC%22">Willey MC</searchLink>; Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Hebden+JN%22">Hebden JN</searchLink>; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Herwaldt+LA%22">Herwaldt LA</searchLink>; Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Gaski+GE%22">Gaski GE</searchLink>; Department of Orthopedic Surgery, Inova Fairfax Medical Campus, Fairfax, Virginia.<br /><searchLink fieldCode="AU" term="%22Kheiri+S%22">Kheiri S</searchLink>; Center for Orthopaedics, Injury, and Research Innovation, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22O'Hara+LM%22">O'Hara LM</searchLink>; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22O'Hara+NN%22">O'Hara NN</searchLink>; Center for Orthopaedics, Injury, and Research Innovation, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Sprague+S%22">Sprague S</searchLink>; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Bzovsky+S%22">Bzovsky S</searchLink>; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Gage+MJ%22">Gage MJ</searchLink>; Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Slobogean+GP%22">Slobogean GP</searchLink>; Center for Orthopaedics, Injury, and Research Innovation, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland.
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