Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity.
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| Title: | Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity. |
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| Authors: | Howden JH; Neuroscience, Physiology and Pharmacology, University College London, London, UK., Hakansson H; Neuroscience, Physiology and Pharmacology, University College London, London, UK., Nieto-Rostro M; Neuroscience, Physiology and Pharmacology, University College London, London, UK., McAdam R; Neuroscience, Biopharmaceutical R&D, AstraZeneca, Cambridge, UK., Arber C; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Brandon NJ; Neuroscience, IMED Biotech Unit, AstraZeneca, Boston, MA, USA., Kittler JT; Neuroscience, Physiology and Pharmacology, University College London, London, UK. Electronic address: j.kittler@ucl.ac.uk. |
| Source: | Cell reports [Cell Rep] 2025 Jun 24; Vol. 44 (6), pp. 115809. Date of Electronic Publication: 2025 Jun 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2211-1247 |
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| DOI: | 10.1016/j.celrep.2025.115809 |