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Buprenorphine-naloxone vs methadone for opioid use disorder: a systematic review and meta-analysis of randomized clinical trials.

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Title: Buprenorphine-naloxone vs methadone for opioid use disorder: a systematic review and meta-analysis of randomized clinical trials.
Authors: Pereira da Silva AM; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil., de Bastos Maximiano ML; Faculty of Medicine, Federal Fluminense University, Rio de janeiro, Brazil., Cabeça LS; Faculty of Medicine, Federal University of Pará, Pará, Brazil., Leal Silva L; Faculty of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Honorato de Faria E; Faculty of Medicine, Federal University of Roraima, Boa Vista, Brazil., Nepomuceno Fernandes M; Faculty of Medicine, Anhembi Morumbi University, São Paulo, Brazil., Barros Mesquita Cunha A; Faculty of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Silva Vieira G; Faculty of Medicine, Federal University of Lavras, Minas Gerais, Brazil., Duarte Ribeiro Sobral T; Faculty of Medicine, Cesmac University Center, Alagoas, Brazil., Vicente de Siqueira Lima Júnior D; Faculty of Medicine, San Diego Biomedical Research Institute, San Diego, CA, USA., Bernadete de Sousa Maia M; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil., de Souza Franco E; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil.
Source: Journal of addictive diseases [J Addict Dis] 2026 Jul-Sep; Vol. 44 (3), pp. 246-256. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Comparative Study; Review
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9107051 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-0848 (Electronic) Linking ISSN: 10550887 NLM ISO Abbreviation: J Addict Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Buprenorphine-naloxone vs methadone for opioid use disorder: a systematic review and meta-analysis of randomized clinical trials.
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  Data: <searchLink fieldCode="AU" term="%22Pereira+da+Silva+AM%22">Pereira da Silva AM</searchLink>; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Bastos+Maximiano+ML%22">de Bastos Maximiano ML</searchLink>; Faculty of Medicine, Federal Fluminense University, Rio de janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Cabeça+LS%22">Cabeça LS</searchLink>; Faculty of Medicine, Federal University of Pará, Pará, Brazil.<br /><searchLink fieldCode="AU" term="%22Leal+Silva+L%22">Leal Silva L</searchLink>; Faculty of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Honorato+de+Faria+E%22">Honorato de Faria E</searchLink>; Faculty of Medicine, Federal University of Roraima, Boa Vista, Brazil.<br /><searchLink fieldCode="AU" term="%22Nepomuceno+Fernandes+M%22">Nepomuceno Fernandes M</searchLink>; Faculty of Medicine, Anhembi Morumbi University, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Barros+Mesquita+Cunha+A%22">Barros Mesquita Cunha A</searchLink>; Faculty of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+Vieira+G%22">Silva Vieira G</searchLink>; Faculty of Medicine, Federal University of Lavras, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Duarte+Ribeiro+Sobral+T%22">Duarte Ribeiro Sobral T</searchLink>; Faculty of Medicine, Cesmac University Center, Alagoas, Brazil.<br /><searchLink fieldCode="AU" term="%22Vicente+de+Siqueira+Lima+Júnior+D%22">Vicente de Siqueira Lima Júnior D</searchLink>; Faculty of Medicine, San Diego Biomedical Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bernadete+de+Sousa+Maia+M%22">Bernadete de Sousa Maia M</searchLink>; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Souza+Franco+E%22">de Souza Franco E</searchLink>; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil.
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  Data: <searchLink fieldCode="JN" term="%229107051%22">Journal of addictive diseases</searchLink> [J Addict Dis] 2026 Jul-Sep; Vol. 44 (3), pp. 246-256. <i>Date of Electronic Publication: </i>2025 Jun 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107051 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1545-0848 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210550887%22">10550887 </searchLink><i>NLM ISO Abbreviation: </i>J Addict Dis <i>Subsets: </i>MEDLINE
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