Ketoconazole Inhibition of Gepirone Biotransformation and Clearance: In Vitro and Clinical Studies.
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| Title: | Ketoconazole Inhibition of Gepirone Biotransformation and Clearance: In Vitro and Clinical Studies. |
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| Authors: | Yang Z; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA., Hossain MA; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Zhang Q; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.; University of Florida College of Pharmacy, Gainesville, FL, USA., Liu L; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA., Singleton CA; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA., Markowitz JS; University of Florida College of Pharmacy, Gainesville, FL, USA.; Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL, USA., Greenblatt DJ; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.; Clinical and Translational Sciences Institute, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA. |
| Source: | Journal of clinical pharmacology [J Clin Pharmacol] 2025 Nov; Vol. 65 (11), pp. 1433-1442. Date of Electronic Publication: 2025 Jun 19. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40536342 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Ketoconazole Inhibition of Gepirone Biotransformation and Clearance: In Vitro and Clinical Studies. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hossain+MA%22">Hossain MA</searchLink>; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.; University of Florida College of Pharmacy, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Singleton+CA%22">Singleton CA</searchLink>; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Markowitz+JS%22">Markowitz JS</searchLink>; University of Florida College of Pharmacy, Gainesville, FL, USA.; Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Greenblatt+DJ%22">Greenblatt DJ</searchLink>; Program in Pharmacology and Drug Development, Tufts University School of Medicine, Boston, MA, USA.; Clinical and Translational Sciences Institute, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220366372%22">Journal of clinical pharmacology</searchLink> [J Clin Pharmacol] 2025 Nov; Vol. 65 (11), pp. 1433-1442. <i>Date of Electronic Publication: </i>2025 Jun 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0366372 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-4604 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200912700%22">00912700 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40536342 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/jcph.70059 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1433 Titles: – TitleFull: Ketoconazole Inhibition of Gepirone Biotransformation and Clearance: In Vitro and Clinical Studies. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yang Z – PersonEntity: Name: NameFull: Hossain MA – PersonEntity: Name: NameFull: Zhang Q – PersonEntity: Name: NameFull: Liu L – PersonEntity: Name: NameFull: Singleton CA – PersonEntity: Name: NameFull: Markowitz JS – PersonEntity: Name: NameFull: Greenblatt DJ IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: 2025 Nov Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1552-4604 Numbering: – Type: volume Value: 65 – Type: issue Value: 11 Titles: – TitleFull: Journal of clinical pharmacology Type: main |
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