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Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in 6- to 11-Year-Olds with Cystic Fibrosis: An Observational Study.

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Title: Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in 6- to 11-Year-Olds with Cystic Fibrosis: An Observational Study.
Authors: Pittman JE; Department of Pediatrics, School of Medicine, Washington University, St. Louis, Missouri., Morgan S; Department of Microbiology, and., McCreary M; Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center and., Vu PT; Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center and., Jorth P; Department of Pathology and Laboratory Medicine.; Department of Medicine, and.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California., Heltshe S; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington.; Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center and.; Center for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, Washington., Hoffman LR; Department of Microbiology, and.; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington.; Center for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, Washington., Kelly A; Division of Endocrinology and Diabetes, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Sagel SD; Department of Pediatrics, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, Colorado., Singh PK; Department of Microbiology, and., Solomon GM; Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama., Rosenfeld M; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington.; Center for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, Washington., Ratjen F; Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.; Translational Medicine, SickKids Research Institute, Toronto, Ontario, Canada; and.; University of Toronto, Toronto, Ontario, Canada.
Corporate Authors: PROMISE Pediatric substudy Investigators
Source: Annals of the American Thoracic Society [Ann Am Thorac Soc] 2025 Nov; Vol. 22 (11), pp. 1696-1708.
Publication Type: Journal Article; Observational Study; Multicenter Study
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 101600811 Publication Model: Print Cited Medium: Internet ISSN: 2325-6621 (Electronic) Linking ISSN: 23256621 NLM ISO Abbreviation: Ann Am Thorac Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in 6- to 11-Year-Olds with Cystic Fibrosis: An Observational Study.
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  Data: <searchLink fieldCode="AU" term="%22Pittman+JE%22">Pittman JE</searchLink>; Department of Pediatrics, School of Medicine, Washington University, St. Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Morgan+S%22">Morgan S</searchLink>; Department of Microbiology, and.<br /><searchLink fieldCode="AU" term="%22McCreary+M%22">McCreary M</searchLink>; Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center and.<br /><searchLink fieldCode="AU" term="%22Vu+PT%22">Vu PT</searchLink>; Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center and.<br /><searchLink fieldCode="AU" term="%22Jorth+P%22">Jorth P</searchLink>; Department of Pathology and Laboratory Medicine.; Department of Medicine, and.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Heltshe+S%22">Heltshe S</searchLink>; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington.; Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center and.; Center for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Hoffman+LR%22">Hoffman LR</searchLink>; Department of Microbiology, and.; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington.; Center for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Kelly+A%22">Kelly A</searchLink>; Division of Endocrinology and Diabetes, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Sagel+SD%22">Sagel SD</searchLink>; Department of Pediatrics, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Singh+PK%22">Singh PK</searchLink>; Department of Microbiology, and.<br /><searchLink fieldCode="AU" term="%22Solomon+GM%22">Solomon GM</searchLink>; Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama.<br /><searchLink fieldCode="AU" term="%22Rosenfeld+M%22">Rosenfeld M</searchLink>; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington.; Center for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Ratjen+F%22">Ratjen F</searchLink>; Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.; Translational Medicine, SickKids Research Institute, Toronto, Ontario, Canada; and.; University of Toronto, Toronto, Ontario, Canada.
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              Text: 2025 Nov
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