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MRAs, SGLT2 Inhibitors, and Kidney Outcomes in CKD and HF: Differences in Diseases, Drugs, or Both?

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Title: MRAs, SGLT2 Inhibitors, and Kidney Outcomes in CKD and HF: Differences in Diseases, Drugs, or Both?
Authors: Mendonça L; Department of Surgery and Physiology, UnIC@RISE, Cardiovascular Research and Development Center, Faculty of Medicine of the University of Porto, Porto, Portugal; Nephrology Department, Unidade Local de Saúde de São João, Porto, Portugal., Neves JS; Department of Surgery and Physiology, UnIC@RISE, Cardiovascular Research and Development Center, Faculty of Medicine of the University of Porto, Porto, Portugal; Endocrinology Department, Unidade Local de Saúde de São João, Porto, Portugal., Testani J; Section of Cardiovascular Medicine, Yale University, Guilford, Connecticut, USA., Zannad F; Centre d'Investigations Cliniques Plurithématique 1433, INSERM, Université de Lorraine, CIC 1439, Institut Lorrain du Coeur et des Vaisseaux, CHU, Vandoeuvre-lès-Nancy and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), INSERM U1116, Centre Hospitalier Régional Universitaire de Nancy, Nancy, France., Ferreira JP; Department of Surgery and Physiology, UnIC@RISE, Cardiovascular Research and Development Center, Faculty of Medicine of the University of Porto, Porto, Portugal; Centre d'Investigations Cliniques Plurithématique 1433, INSERM, Université de Lorraine, CIC 1439, Institut Lorrain du Coeur et des Vaisseaux, CHU, Vandoeuvre-lès-Nancy and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), INSERM U1116, Centre Hospitalier Régional Universitaire de Nancy, Nancy, France; Heart Failure Clinic, Internal Medicine Department, Unidade Local de Saúde de Gaia/Espinho, Gaia, Portugal. Electronic address: jpferreira@med.up.pt.
Source: JACC. Heart failure [JACC Heart Fail] 2025 Aug; Vol. 13 (8), pp. 102514. Date of Electronic Publication: 2025 Jun 20.
Publication Type: Editorial
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101598241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-1787 (Electronic) Linking ISSN: 22131779 NLM ISO Abbreviation: JACC Heart Fail Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: MRAs, SGLT2 Inhibitors, and Kidney Outcomes in CKD and HF: Differences in Diseases, Drugs, or Both?
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  Data: <searchLink fieldCode="AU" term="%22Mendonça+L%22">Mendonça L</searchLink>; Department of Surgery and Physiology, UnIC@RISE, Cardiovascular Research and Development Center, Faculty of Medicine of the University of Porto, Porto, Portugal; Nephrology Department, Unidade Local de Saúde de São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Neves+JS%22">Neves JS</searchLink>; Department of Surgery and Physiology, UnIC@RISE, Cardiovascular Research and Development Center, Faculty of Medicine of the University of Porto, Porto, Portugal; Endocrinology Department, Unidade Local de Saúde de São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Testani+J%22">Testani J</searchLink>; Section of Cardiovascular Medicine, Yale University, Guilford, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Zannad+F%22">Zannad F</searchLink>; Centre d'Investigations Cliniques Plurithématique 1433, INSERM, Université de Lorraine, CIC 1439, Institut Lorrain du Coeur et des Vaisseaux, CHU, Vandoeuvre-lès-Nancy and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), INSERM U1116, Centre Hospitalier Régional Universitaire de Nancy, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Ferreira+JP%22">Ferreira JP</searchLink>; Department of Surgery and Physiology, UnIC@RISE, Cardiovascular Research and Development Center, Faculty of Medicine of the University of Porto, Porto, Portugal; Centre d'Investigations Cliniques Plurithématique 1433, INSERM, Université de Lorraine, CIC 1439, Institut Lorrain du Coeur et des Vaisseaux, CHU, Vandoeuvre-lès-Nancy and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), INSERM U1116, Centre Hospitalier Régional Universitaire de Nancy, Nancy, France; Heart Failure Clinic, Internal Medicine Department, Unidade Local de Saúde de Gaia/Espinho, Gaia, Portugal. Electronic address: jpferreira@med.up.pt.
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  Data: <searchLink fieldCode="JN" term="%22101598241%22">JACC. Heart failure</searchLink> [JACC Heart Fail] 2025 Aug; Vol. 13 (8), pp. 102514. <i>Date of Electronic Publication: </i>2025 Jun 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101598241 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2213-1787 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222131779%22">22131779 </searchLink><i>NLM ISO Abbreviation: </i>JACC Heart Fail <i>Subsets: </i>MEDLINE; In Process
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        Value: 10.1016/j.jchf.2025.102514
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              Text: 2025 Aug
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