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Novel Kinesin Family Member 1A Variants Linked to Atypical Parkinsonism Elicit Altered Neuronal Transactive Response DNA Binding Protein 43 kDa Interactions and Dendritic Atrophy.

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Title: Novel Kinesin Family Member 1A Variants Linked to Atypical Parkinsonism Elicit Altered Neuronal Transactive Response DNA Binding Protein 43 kDa Interactions and Dendritic Atrophy.
Authors: Homayoun H; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., DeChellis-Marks MR; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania., Kofler J; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Fricklas G; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Gleixner AM; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Yeh FC; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Lacomis D; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Chu CT; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address: ctc4@pitt.edu., Donnelly CJ; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: cjdon25@pitt.edu.
Source: The American journal of pathology [Am J Pathol] 2025 Nov; Vol. 195 (11), pp. 2161-2175. Date of Electronic Publication: 2025 Jun 19.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0370502 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-2191 (Electronic) Linking ISSN: 00029440 NLM ISO Abbreviation: Am J Pathol Subsets: MEDLINE
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  Data: Novel Kinesin Family Member 1A Variants Linked to Atypical Parkinsonism Elicit Altered Neuronal Transactive Response DNA Binding Protein 43 kDa Interactions and Dendritic Atrophy.
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  Data: <searchLink fieldCode="AU" term="%22Homayoun+H%22">Homayoun H</searchLink>; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22DeChellis-Marks+MR%22">DeChellis-Marks MR</searchLink>; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Kofler+J%22">Kofler J</searchLink>; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Fricklas+G%22">Fricklas G</searchLink>; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Gleixner+AM%22">Gleixner AM</searchLink>; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Yeh+FC%22">Yeh FC</searchLink>; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Lacomis+D%22">Lacomis D</searchLink>; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Chu+CT%22">Chu CT</searchLink>; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address: ctc4@pitt.edu.<br /><searchLink fieldCode="AU" term="%22Donnelly+CJ%22">Donnelly CJ</searchLink>; Department of Neurobiology, LiveLikeLou Center for ALS Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: cjdon25@pitt.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370502 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-2191 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200029440%22">00029440 </searchLink><i>NLM ISO Abbreviation: </i>Am J Pathol <i>Subsets: </i>MEDLINE
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