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Identification of cerebrospinal fluid pharmacodynamic biomarkers and molecular correlates of brain activity in a Phase 2 clinical trial of the Alzheimer's disease drug candidate CT1812.

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Title: Identification of cerebrospinal fluid pharmacodynamic biomarkers and molecular correlates of brain activity in a Phase 2 clinical trial of the Alzheimer's disease drug candidate CT1812.
Authors: Di Caro V; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Cho E; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., North HA; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Caldwell J; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Pandey K; Systems Biology Emtherapro Inc Atlanta Georgia USA., Duong D; Department of Biochemistry Emory University School of Medicine Atlanta Georgia USA., Grundman M; Global R&D Partners, LLC San Diego California USA.; Department of Neurosciences University of California San Diego California USA., de Haan W; Department of Neurology Alzheimer Center VU University Medical Center Amsterdam The Netherlands., Vijverberg EG; Department of Neurology Alzheimer Center VU University Medical Center Amsterdam The Netherlands., Teunissen CE; Department of Laboratory Medicine VU University Medical Center Amsterdam The Netherlands., Caggiano AO; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Seyfried NT; Department of Biochemistry Emory University School of Medicine Atlanta Georgia USA., Hamby ME; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.
Source: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2025 Jun 19; Vol. 11 (2), pp. e70119. Date of Electronic Publication: 2025 Jun 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of cerebrospinal fluid pharmacodynamic biomarkers and molecular correlates of brain activity in a Phase 2 clinical trial of the Alzheimer's disease drug candidate CT1812.
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  Data: <searchLink fieldCode="AU" term="%22Di+Caro+V%22">Di Caro V</searchLink>; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.<br /><searchLink fieldCode="AU" term="%22Cho+E%22">Cho E</searchLink>; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.<br /><searchLink fieldCode="AU" term="%22North+HA%22">North HA</searchLink>; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.<br /><searchLink fieldCode="AU" term="%22Caldwell+J%22">Caldwell J</searchLink>; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.<br /><searchLink fieldCode="AU" term="%22Pandey+K%22">Pandey K</searchLink>; Systems Biology Emtherapro Inc Atlanta Georgia USA.<br /><searchLink fieldCode="AU" term="%22Duong+D%22">Duong D</searchLink>; Department of Biochemistry Emory University School of Medicine Atlanta Georgia USA.<br /><searchLink fieldCode="AU" term="%22Grundman+M%22">Grundman M</searchLink>; Global R&D Partners, LLC San Diego California USA.; Department of Neurosciences University of California San Diego California USA.<br /><searchLink fieldCode="AU" term="%22de+Haan+W%22">de Haan W</searchLink>; Department of Neurology Alzheimer Center VU University Medical Center Amsterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vijverberg+EG%22">Vijverberg EG</searchLink>; Department of Neurology Alzheimer Center VU University Medical Center Amsterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Teunissen+CE%22">Teunissen CE</searchLink>; Department of Laboratory Medicine VU University Medical Center Amsterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Caggiano+AO%22">Caggiano AO</searchLink>; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.<br /><searchLink fieldCode="AU" term="%22Seyfried+NT%22">Seyfried NT</searchLink>; Department of Biochemistry Emory University School of Medicine Atlanta Georgia USA.<br /><searchLink fieldCode="AU" term="%22Hamby+ME%22">Hamby ME</searchLink>; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.
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  Data: <searchLink fieldCode="JN" term="%22101650118%22">Alzheimer's & dementia (New York, N. Y.)</searchLink> [Alzheimers Dement (N Y)] 2025 Jun 19; Vol. 11 (2), pp. e70119. <i>Date of Electronic Publication: </i>2025 Jun 19 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Alzheimer's+Association%22">Wiley on behalf of the Alzheimer's Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101650118 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-8737 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223528737%22">23528737 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement (N Y) <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40547328
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              Text: 2025 Jun 19
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