Identification of cerebrospinal fluid pharmacodynamic biomarkers and molecular correlates of brain activity in a Phase 2 clinical trial of the Alzheimer's disease drug candidate CT1812.

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Title: Identification of cerebrospinal fluid pharmacodynamic biomarkers and molecular correlates of brain activity in a Phase 2 clinical trial of the Alzheimer's disease drug candidate CT1812.
Authors: Di Caro V; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Cho E; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., North HA; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Caldwell J; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Pandey K; Systems Biology Emtherapro Inc Atlanta Georgia USA., Duong D; Department of Biochemistry Emory University School of Medicine Atlanta Georgia USA., Grundman M; Global R&D Partners, LLC San Diego California USA.; Department of Neurosciences University of California San Diego California USA., de Haan W; Department of Neurology Alzheimer Center VU University Medical Center Amsterdam The Netherlands., Vijverberg EG; Department of Neurology Alzheimer Center VU University Medical Center Amsterdam The Netherlands., Teunissen CE; Department of Laboratory Medicine VU University Medical Center Amsterdam The Netherlands., Caggiano AO; Research Cognition Therapeutics Pittsburgh Pennsylvania USA., Seyfried NT; Department of Biochemistry Emory University School of Medicine Atlanta Georgia USA., Hamby ME; Research Cognition Therapeutics Pittsburgh Pennsylvania USA.
Source: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2025 Jun 19; Vol. 11 (2), pp. e70119. Date of Electronic Publication: 2025 Jun 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2352-8737
DOI:10.1002/trc2.70119