E-cadherin negatively regulates hESCs endodermal differentiation under varied substrate stiffnesses.

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Title: E-cadherin negatively regulates hESCs endodermal differentiation under varied substrate stiffnesses.
Authors: Zhang F; Center for Biomechanics and Bioengineering, Beijing Key Laboratory of Engineered Construction and Mechanobiology and Key Laboratory of Microgravity, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China.; School of Engineering Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.; Medical Morphology Teaching Laboratory, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China., Zheng L; Center for Biomechanics and Bioengineering, Beijing Key Laboratory of Engineered Construction and Mechanobiology and Key Laboratory of Microgravity, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China.; School of Engineering Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China., Wu Y; Center for Biomechanics and Bioengineering, Beijing Key Laboratory of Engineered Construction and Mechanobiology and Key Laboratory of Microgravity, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China.; School of Engineering Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China., Ding Q; Center for Biomechanics and Bioengineering, Beijing Key Laboratory of Engineered Construction and Mechanobiology and Key Laboratory of Microgravity, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China.; School of Engineering Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China., Lü S; Center for Biomechanics and Bioengineering, Beijing Key Laboratory of Engineered Construction and Mechanobiology and Key Laboratory of Microgravity, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China.; School of Engineering Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China., Lü D; Center for Biomechanics and Bioengineering, Beijing Key Laboratory of Engineered Construction and Mechanobiology and Key Laboratory of Microgravity, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China. lvdongy@imech.ac.cn.; School of Engineering Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China. lvdongy@imech.ac.cn., Long M; Center for Biomechanics and Bioengineering, Beijing Key Laboratory of Engineered Construction and Mechanobiology and Key Laboratory of Microgravity, Institute of Mechanics, Chinese Academy of Sciences, Beijing, 100190, China. mlong@imech.ac.cn.; School of Engineering Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China. mlong@imech.ac.cn.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Jun 23; Vol. 82 (1), pp. 245. Date of Electronic Publication: 2025 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-025-05776-9