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Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures.

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Title: Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures.
Authors: Converse A; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America., Perry MJ; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America., Dipali SS; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America., Isola JVV; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America., Kelly EB; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America., Varberg JM; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America., Zelinski MB; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America., Stout MB; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, Oklahoma, United States of America., Pritchard MT; Department of Pharmacology, Toxicology & Therapeutics University of Kansas Medical Center, Kansas City, Kansas, United States of America.; Institute for Reproductive and Developmental Sciences, University of Kansas Medical Center, Kansas City, Kansas, United States of America., Duncan FE; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
Source: PLoS biology [PLoS Biol] 2025 Jun 23; Vol. 23 (6), pp. e3003204. Date of Electronic Publication: 2025 Jun 23 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures.
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  Data: <searchLink fieldCode="AU" term="%22Converse+A%22">Converse A</searchLink>; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Perry+MJ%22">Perry MJ</searchLink>; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Dipali+SS%22">Dipali SS</searchLink>; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Isola+JVV%22">Isola JVV</searchLink>; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.<br /><searchLink fieldCode="AU" term="%22Kelly+EB%22">Kelly EB</searchLink>; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.<br /><searchLink fieldCode="AU" term="%22Varberg+JM%22">Varberg JM</searchLink>; Stowers Institute for Medical Research, Kansas City, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Zelinski+MB%22">Zelinski MB</searchLink>; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Stout+MB%22">Stout MB</searchLink>; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, Oklahoma, United States of America.<br /><searchLink fieldCode="AU" term="%22Pritchard+MT%22">Pritchard MT</searchLink>; Department of Pharmacology, Toxicology & Therapeutics University of Kansas Medical Center, Kansas City, Kansas, United States of America.; Institute for Reproductive and Developmental Sciences, University of Kansas Medical Center, Kansas City, Kansas, United States of America.<br /><searchLink fieldCode="AU" term="%22Duncan+FE%22">Duncan FE</searchLink>; Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2025 Jun 23; Vol. 23 (6), pp. e3003204. <i>Date of Electronic Publication: </i>2025 Jun 23 (<i>Print Publication: </i>2025).
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