Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes.

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Title: Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes.
Authors: Nagaraj H; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA., Jeon T; Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, 230 Stockbridge Road, Amherst, MA, 01003, USA., Cicek YA; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA., Goswami R; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA., Nasim N; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA., Mhaske R; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA., Rotello VM; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA. rotello@chem.umass.edu.
Source: Pharmaceutical research [Pharm Res] 2025 Dec; Vol. 42 (12), pp. 2369-2377. Date of Electronic Publication: 2025 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Nagaraj+H%22">Nagaraj H</searchLink>; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA.<br /><searchLink fieldCode="AU" term="%22Jeon+T%22">Jeon T</searchLink>; Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, 230 Stockbridge Road, Amherst, MA, 01003, USA.<br /><searchLink fieldCode="AU" term="%22Cicek+YA%22">Cicek YA</searchLink>; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA.<br /><searchLink fieldCode="AU" term="%22Goswami+R%22">Goswami R</searchLink>; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA.<br /><searchLink fieldCode="AU" term="%22Nasim+N%22">Nasim N</searchLink>; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA.<br /><searchLink fieldCode="AU" term="%22Mhaske+R%22">Mhaske R</searchLink>; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA.<br /><searchLink fieldCode="AU" term="%22Rotello+VM%22">Rotello VM</searchLink>; Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA. rotello@chem.umass.edu.
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  Data: <searchLink fieldCode="JN" term="%228406521%22">Pharmaceutical research</searchLink> [Pharm Res] 2025 Dec; Vol. 42 (12), pp. 2369-2377. <i>Date of Electronic Publication: </i>2025 Jun 23.
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        Value: 10.1007/s11095-025-03884-6
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      – TitleFull: Efficient Cytosolic Delivery of siRNA Using Lyophilized and Reconstituted Polymer-siRNA Polyplexes.
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              Text: 2025 Dec
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