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Combined prognostic impact of initial clinical stage and residual cancer burden after neoadjuvant systemic therapy in triple-negative and HER2-positive breast cancer: an analysis of the I-SPY2 randomized clinical trial.

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Title: Combined prognostic impact of initial clinical stage and residual cancer burden after neoadjuvant systemic therapy in triple-negative and HER2-positive breast cancer: an analysis of the I-SPY2 randomized clinical trial.
Authors: Leon-Ferre RA; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA. leonferre.roberto@mayo.edu.; Department of Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. leonferre.roberto@mayo.edu., Dimitroff K; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Yau C; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Giridhar KV; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA., Mukhtar R; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Hirst G; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Hylton N; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Perlmutter J; Gemini Group, Ann Arbor, Michigan, USA., DeMichele A; University of Pennsylvania, Philadelphia, PA, USA., Yee D; University of Minnesota, Minneapolis, MN, USA., van 't Veer L; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Rugo H; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Symmans WF; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Goetz MP; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA., Esserman L; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Boughey JC; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.
Source: Breast cancer research : BCR [Breast Cancer Res] 2025 Jun 23; Vol. 27 (1), pp. 115. Date of Electronic Publication: 2025 Jun 23.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Combined prognostic impact of initial clinical stage and residual cancer burden after neoadjuvant systemic therapy in triple-negative and HER2-positive breast cancer: an analysis of the I-SPY2 randomized clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Leon-Ferre+RA%22">Leon-Ferre RA</searchLink>; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA. leonferre.roberto@mayo.edu.; Department of Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. leonferre.roberto@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Dimitroff+K%22">Dimitroff K</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yau+C%22">Yau C</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Giridhar+KV%22">Giridhar KV</searchLink>; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Mukhtar+R%22">Mukhtar R</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hirst+G%22">Hirst G</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hylton+N%22">Hylton N</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Perlmutter+J%22">Perlmutter J</searchLink>; Gemini Group, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22DeMichele+A%22">DeMichele A</searchLink>; University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Yee+D%22">Yee D</searchLink>; University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22van+'t+Veer+L%22">van 't Veer L</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rugo+H%22">Rugo H</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Symmans+WF%22">Symmans WF</searchLink>; University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Goetz+MP%22">Goetz MP</searchLink>; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Esserman+L%22">Esserman L</searchLink>; University of California San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Boughey+JC%22">Boughey JC</searchLink>; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.
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  Data: <searchLink fieldCode="JN" term="%22100927353%22">Breast cancer research : BCR</searchLink> [Breast Cancer Res] 2025 Jun 23; Vol. 27 (1), pp. 115. <i>Date of Electronic Publication: </i>2025 Jun 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100927353 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1465-542X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214655411%22">14655411 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res <i>Subsets: </i>MEDLINE
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