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AAnet Resolves a Continuum of Spatially Localized Cell States to Unveil Intratumoral Heterogeneity.

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Title: AAnet Resolves a Continuum of Spatially Localized Cell States to Unveil Intratumoral Heterogeneity.
Authors: Venkat A; Computational Biology and Bioinformatics Program, Yale University, New Haven, Connecticut.; Broad Institute at MIT and Harvard, Cambridge, Massachusetts., Youlten SE; Department of Genetics, Yale School of Medicine, New Haven, Connecticut., San Juan BP; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia., Purcell CA; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia., Gupta S; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia., Amodio M; Broad Institute at MIT and Harvard, Cambridge, Massachusetts.; Department of Computer Science, Yale University, New Haven, Connecticut., Neumann DP; University of New South Wales, Kensington, Australia., Lock JG; University of New South Wales, Kensington, Australia., Westacott AE; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia., McCool CS; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia., Burkhardt DB; Department of Genetics, Yale School of Medicine, New Haven, Connecticut.; NVIDIA, Toronto, Canada., Benz A; Cellarity, Somerville, Massachusetts.; Department of Mathematics, Yale University, New Haven, Connecticut., Mollbrink A; SciLifeLab, KTH Royal Institute of Technology, Stockholm, Sweden., Lundeberg J; SciLifeLab, KTH Royal Institute of Technology, Stockholm, Sweden., van Dijk D; Computational Biology and Bioinformatics Program, Yale University, New Haven, Connecticut.; Department of Computer Science, Yale University, New Haven, Connecticut.; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut., Holst J; University of New South Wales, Kensington, Australia., Goldstein LD; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia., Kummerfeld S; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia., Krishnaswamy S; Computational Biology and Bioinformatics Program, Yale University, New Haven, Connecticut.; Department of Genetics, Yale School of Medicine, New Haven, Connecticut.; Department of Computer Science, Yale University, New Haven, Connecticut.; Applied Mathematics Program, Yale University, New Haven, Connecticut., Chaffer CL; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.
Source: Cancer discovery [Cancer Discov] 2025 Oct 06; Vol. 15 (10), pp. 2139-2165.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Venkat+A%22">Venkat A</searchLink>; Computational Biology and Bioinformatics Program, Yale University, New Haven, Connecticut.; Broad Institute at MIT and Harvard, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Youlten+SE%22">Youlten SE</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22San+Juan+BP%22">San Juan BP</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Purcell+CA%22">Purcell CA</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Amodio+M%22">Amodio M</searchLink>; Broad Institute at MIT and Harvard, Cambridge, Massachusetts.; Department of Computer Science, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Neumann+DP%22">Neumann DP</searchLink>; University of New South Wales, Kensington, Australia.<br /><searchLink fieldCode="AU" term="%22Lock+JG%22">Lock JG</searchLink>; University of New South Wales, Kensington, Australia.<br /><searchLink fieldCode="AU" term="%22Westacott+AE%22">Westacott AE</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22McCool+CS%22">McCool CS</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Burkhardt+DB%22">Burkhardt DB</searchLink>; Department of Genetics, Yale School of Medicine, New Haven, Connecticut.; NVIDIA, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Benz+A%22">Benz A</searchLink>; Cellarity, Somerville, Massachusetts.; Department of Mathematics, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Mollbrink+A%22">Mollbrink A</searchLink>; SciLifeLab, KTH Royal Institute of Technology, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Lundeberg+J%22">Lundeberg J</searchLink>; SciLifeLab, KTH Royal Institute of Technology, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22van+Dijk+D%22">van Dijk D</searchLink>; Computational Biology and Bioinformatics Program, Yale University, New Haven, Connecticut.; Department of Computer Science, Yale University, New Haven, Connecticut.; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Holst+J%22">Holst J</searchLink>; University of New South Wales, Kensington, Australia.<br /><searchLink fieldCode="AU" term="%22Goldstein+LD%22">Goldstein LD</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Kummerfeld+S%22">Kummerfeld S</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.<br /><searchLink fieldCode="AU" term="%22Krishnaswamy+S%22">Krishnaswamy S</searchLink>; Computational Biology and Bioinformatics Program, Yale University, New Haven, Connecticut.; Department of Genetics, Yale School of Medicine, New Haven, Connecticut.; Department of Computer Science, Yale University, New Haven, Connecticut.; Applied Mathematics Program, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Chaffer+CL%22">Chaffer CL</searchLink>; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, Australia.; St Vincent's Clinical School, University of New South Wales Medicine, University of New South Wales, Darlinghurst, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2025 Oct 06; Vol. 15 (10), pp. 2139-2165.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101561693 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2159-8290 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221598274%22">21598274 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Discov <i>Subsets: </i>MEDLINE
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