Enhancement of tacrolimus production in Streptomyces tsukubaensis by genetic engineering and process optimization.
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| Title: | Enhancement of tacrolimus production in Streptomyces tsukubaensis by genetic engineering and process optimization. |
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| Authors: | Zhang J; National Key Laboratory of Lead Druggability Research, China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical Industry, 285 Gebaini Road, Pudong, Shanghai, 201203, P. R. China., Huang H; National Key Laboratory of Lead Druggability Research, China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical Industry, 285 Gebaini Road, Pudong, Shanghai, 201203, P. R. China., Zhang Z; Department of Biological Medicines & Shanghai Engineering Research Center of Immunotherapeutics, Fudan University School of Pharmacy, 826 Zhangheng Road, Pudong, Shanghai, 201203, P. R. China., Tang J; National Key Laboratory of Lead Druggability Research, China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical Industry, 285 Gebaini Road, Pudong, Shanghai, 201203, P. R. China., Gui J; National Key Laboratory of Lead Druggability Research, China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical Industry, 285 Gebaini Road, Pudong, Shanghai, 201203, P. R. China., Yang S; National Key Laboratory of Lead Druggability Research, China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical Industry, 285 Gebaini Road, Pudong, Shanghai, 201203, P. R. China., Chen S; National Key Laboratory of Lead Druggability Research, China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical Industry, 285 Gebaini Road, Pudong, Shanghai, 201203, P. R. China. sxzlb@263.net. |
| Source: | World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2025 Jun 25; Vol. 41 (7), pp. 224. Date of Electronic Publication: 2025 Jun 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Germany NLM ID: 9012472 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-0972 (Electronic) Linking ISSN: 09593993 NLM ISO Abbreviation: World J Microbiol Biotechnol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1573-0972 |
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| DOI: | 10.1007/s11274-025-04410-x |
