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Identification of an Induced Orthosteric Pocket in IL-23: A New Avenue for Non-biological Therapeutic Targeting.

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Title: Identification of an Induced Orthosteric Pocket in IL-23: A New Avenue for Non-biological Therapeutic Targeting.
Authors: Lecomte FC; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Joseph JS; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Stalewski J; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Shen Q; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Arnoult E; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Sridhar V; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Liu M; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Hu Y; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Gasendo JG; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Ben Arie H; Bio-Technology General Ltd, Be'er Tuvia Industrial Zone, P.O., Kiryat Malachi 8310402, Israel., Keinan N; Bio-Technology General Ltd, Be'er Tuvia Industrial Zone, P.O., Kiryat Malachi 8310402, Israel., Keidar L; Bio-Technology General Ltd, Be'er Tuvia Industrial Zone, P.O., Kiryat Malachi 8310402, Israel., Aviv I; Bio-Technology General Ltd, Be'er Tuvia Industrial Zone, P.O., Kiryat Malachi 8310402, Israel., Ruvinov E; Bio-Technology General Ltd, Be'er Tuvia Industrial Zone, P.O., Kiryat Malachi 8310402, Israel., Grandjean J; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Dores-Silva PR; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Mak A; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Santoso B; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Kim S; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Shende V; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Wever WJ; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Mirzadegan T; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Zhu Z; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Fuchs B; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States., Pinton P; Ferring International PharmaScience Center, Amager Strandvej 405, Kastrup 2770, Denmark., Szabady R; Ferring Research Institute, 4245 Sorrento Valley Blvd, San Diego, California CA92121, United States.
Source: ACS chemical biology [ACS Chem Biol] 2025 Jul 18; Vol. 20 (7), pp. 1609-1618. Date of Electronic Publication: 2025 Jun 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of an Induced Orthosteric Pocket in IL-23: A New Avenue for Non-biological Therapeutic Targeting.
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  Data: <searchLink fieldCode="JN" term="%22101282906%22">ACS chemical biology</searchLink> [ACS Chem Biol] 2025 Jul 18; Vol. 20 (7), pp. 1609-1618. <i>Date of Electronic Publication: </i>2025 Jun 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101282906 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1554-8937 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215548929%22">15548929 </searchLink><i>NLM ISO Abbreviation: </i>ACS Chem Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acschembio.5c00181
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        Text: English
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              Text: 2025 Jul 18
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