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Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function.

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Title: Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function.
Authors: Mills KJ; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America., Doyle M; Department of Chemistry, North Carolina State University, Raleigh, North Carolina, United States of America., House JS; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.; Graduate Program in Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America.; National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, United States of America., Witherspoon JG; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America., Krakko D; Molecular Education, Technology and Research Innovation Center (METRIC), North Carolina State University, Raleigh, North Carolina, United States of America., Stutts WL; Molecular Education, Technology and Research Innovation Center (METRIC), North Carolina State University, Raleigh, North Carolina, United States of America.; Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina, United States of America., Chappel JR; Bioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America., Hall JR; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.; Graduate Program in Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America., Baker ES; Department of Chemistry, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America.; Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America., Smart RC; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.; Graduate Program in Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America.
Source: PloS one [PLoS One] 2025 Jun 25; Vol. 20 (6), pp. e0326670. Date of Electronic Publication: 2025 Jun 25 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function.
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  Data: <searchLink fieldCode="AU" term="%22Mills+KJ%22">Mills KJ</searchLink>; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Doyle+M%22">Doyle M</searchLink>; Department of Chemistry, North Carolina State University, Raleigh, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22House+JS%22">House JS</searchLink>; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.; Graduate Program in Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America.; National Institute of Environmental Health Sciences, Research Triangle Park, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Witherspoon+JG%22">Witherspoon JG</searchLink>; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Krakko+D%22">Krakko D</searchLink>; Molecular Education, Technology and Research Innovation Center (METRIC), North Carolina State University, Raleigh, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Stutts+WL%22">Stutts WL</searchLink>; Molecular Education, Technology and Research Innovation Center (METRIC), North Carolina State University, Raleigh, North Carolina, United States of America.; Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Chappel+JR%22">Chappel JR</searchLink>; Bioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Hall+JR%22">Hall JR</searchLink>; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.; Graduate Program in Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Baker+ES%22">Baker ES</searchLink>; Department of Chemistry, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America.; Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Smart+RC%22">Smart RC</searchLink>; Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, United States of America.; Graduate Program in Toxicology, North Carolina State University, Raleigh, North Carolina, United States of America.; Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2025 Jun 25; Vol. 20 (6), pp. e0326670. <i>Date of Electronic Publication: </i>2025 Jun 25 (<i>Print Publication: </i>2025).
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