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Development of a BRET based chloride biosensor for high throughput screening of KCC2 modulators.

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Title: Development of a BRET based chloride biosensor for high throughput screening of KCC2 modulators.
Authors: Lay CS; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK. Electronic address: charlie.lay@omass.com., Diamantopoulou E; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK., Dürr KL; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK., Liko I; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK., Charlton SJ; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK.
Source: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2025 Sep; Vol. 35, pp. 100245. Date of Electronic Publication: 2025 Jun 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697563 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-5560 (Electronic) Linking ISSN: 24725552 NLM ISO Abbreviation: SLAS Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Development of a BRET based chloride biosensor for high throughput screening of KCC2 modulators.
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  Data: <searchLink fieldCode="AU" term="%22Lay+CS%22">Lay CS</searchLink>; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK. Electronic address: charlie.lay@omass.com.<br /><searchLink fieldCode="AU" term="%22Diamantopoulou+E%22">Diamantopoulou E</searchLink>; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK.<br /><searchLink fieldCode="AU" term="%22Dürr+KL%22">Dürr KL</searchLink>; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK.<br /><searchLink fieldCode="AU" term="%22Liko+I%22">Liko I</searchLink>; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK.<br /><searchLink fieldCode="AU" term="%22Charlton+SJ%22">Charlton SJ</searchLink>; OMass Therapeutics, Building 4000, John Smith Dr, ARC, Oxford, OX4 2GX, UK.
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  Data: <searchLink fieldCode="JN" term="%22101697563%22">SLAS discovery : advancing life sciences R & D</searchLink> [SLAS Discov] 2025 Sep; Vol. 35, pp. 100245. <i>Date of Electronic Publication: </i>2025 Jun 24.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101697563 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2472-5560 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224725552%22">24725552 </searchLink><i>NLM ISO Abbreviation: </i>SLAS Discov <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.slasd.2025.100245
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      – Code: eng
        Text: English
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      – TitleFull: Development of a BRET based chloride biosensor for high throughput screening of KCC2 modulators.
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            NameFull: Lay CS
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            NameFull: Diamantopoulou E
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            – D: 01
              M: 09
              Text: 2025 Sep
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              Value: 35
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            – TitleFull: SLAS discovery : advancing life sciences R & D
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