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LRRC8A/PKC/FLNA pathway activation is detrimental to colon cancer patients.

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Title: LRRC8A/PKC/FLNA pathway activation is detrimental to colon cancer patients.
Authors: Liu R; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China., Zhao L; Department of Gynecology and Obstetrics, Shanxi Provincial People's Hospital, Taiyuan, China.; School of Chemistry, Xi'an Jiaotong University, Xi'an, China., Cui S; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China., Pouranfard M; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China., Jing Z; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China., Ren Y; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China., Zhao W; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China., Zhou D; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China. zhoudx@xjtu.edu.cn., Zhang H; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China. zhf19841011@xjtu.edu.cn.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China. zhf19841011@xjtu.edu.cn.
Source: Functional & integrative genomics [Funct Integr Genomics] 2025 Jun 27; Vol. 25 (1), pp. 138. Date of Electronic Publication: 2025 Jun 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 100939343 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-7948 (Electronic) Linking ISSN: 1438793X NLM ISO Abbreviation: Funct Integr Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: LRRC8A/PKC/FLNA pathway activation is detrimental to colon cancer patients.
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  Data: <searchLink fieldCode="AU" term="%22Liu+R%22">Liu R</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Gynecology and Obstetrics, Shanxi Provincial People's Hospital, Taiyuan, China.; School of Chemistry, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Cui+S%22">Cui S</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Pouranfard+M%22">Pouranfard M</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Jing+Z%22">Jing Z</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China.<br /><searchLink fieldCode="AU" term="%22Zhou+D%22">Zhou D</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China. zhoudx@xjtu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Pathology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an Jiaotong University, No.76 Yanta West Road, Xi'an, 710061, Shaanxi Province, China. zhf19841011@xjtu.edu.cn.; Institute of Genetics and Developmental Biology, Translational Medicine Institute, Xi'an Jiaotong University, Xi'an, China. zhf19841011@xjtu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100939343%22">Functional & integrative genomics</searchLink> [Funct Integr Genomics] 2025 Jun 27; Vol. 25 (1), pp. 138. <i>Date of Electronic Publication: </i>2025 Jun 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>100939343 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1438-7948 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221438793X%22">1438793X </searchLink><i>NLM ISO Abbreviation: </i>Funct Integr Genomics <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10142-025-01650-w
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      – TitleFull: LRRC8A/PKC/FLNA pathway activation is detrimental to colon cancer patients.
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              Text: 2025 Jun 27
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